Biomechanical response of the bovine pia-arachnoid complex to tensile loading at varying strain-rates.
Biomechanical response of the bovine pia-arachnoid complex to tensile loading at varying strain-rates.
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DOI：
10.4271/2006-22-0025
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发表时间：
2006-11
影响因子：
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通讯作者：
X. Jin;Jong B. Lee;L. Leung;Liying Zhang;King H. Yang;A. King
中科院分区：
文献类型：
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作者：
X. Jin;Jong B. Lee;L. Leung;Liying Zhang;King H. Yang;A. King
覆盖大脑的软膜-蛛网膜复合体（PAC）在大脑受到冲击或惯性载荷时的力学响应中起着重要作用。然而，软膜-蛛网膜复合体的机械特性及其对大脑整体反应的影响尚未得到很好的表征。因此，有限元（FE）脑模型往往过于简化的反应的软膜-蛛网膜复合体，可能会导致损失的准确性模型预测。本研究的目的是确定，实验，在准静态和动态载荷条件下的软膜-蛛网膜复合体的材料特性。从新鲜屠宰的牛受试者的顶骨和颞区获得软膜-蛛网膜复合体的标本，并记录标本的方向。在应变率为0.05、0.5、5和100 s（-1）（每组n = 10）下进行单冲程、单轴准静态和动态拉伸实验。还研究了软膜-蛛网膜复合体的方向差异。本研究的结果显示，软脑膜-蛛网膜复合体具有速率依赖性和各向同性，表明软脑膜-蛛网膜复合体在撞击过程中可以为邻近的脑组织提供全方位的支撑和承载。
The pia-arachnoid complex (PAC) covering the brain plays an important role in the mechanical response of the brain due to impact or inertial loading. However, the mechanical properties of the pia-arachnoid complex and its influence on the overall response of the brain have not been well characterized. Consequently, finite element (FE) brain models have tended to oversimplify the response of the pia-arachnoid complex, possibly resulting in a loss of accuracy in the model predictions. The aim of this study was to determine, experimentally, the material properties of the pia-arachnoid complex under quasi-static and dynamic loading conditions. Specimens of the pia-arachnoid complex were obtained from the parietal and temporal regions of freshly slaughtered bovine subjects with the specimen orientation recorded. Single-stroke, uniaxial quasi-static and dynamic tensile experiments were performed at strain-rates of 0.05, 0.5, 5 and 100 s(-1) (n = 10 for each strain rate group). Directional differences of the pia-arachnoid complex were also investigated. Results from this study revealed the pia-arachnoid complex was rate-dependent and isotropic, suggesting that the pia-arachnoid complex can provide omnidirectional support and load bearing to the adjacent brain tissue during an impact.