Ageing in higher functioning adults with Down's syndrome: an interim report in a longitudinal study.
Ageing in higher functioning adults with Down's syndrome: an interim report in a longitudinal study.
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患有唐氏综合症的高功能成人的衰老：纵向研究的中期报告。
DOI：
10.1111/j.1365-2788.1992.tb00511.x
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发表时间：
1992
期刊：
影响因子：
--
通讯作者：
Wisniewski,KE
中科院分区：
文献类型：
--
作者：
Devenny,DA;Hill,AL;Patxot,O;Silverman,WP;Wisniewski,KE
研究人员对居住在社区的轻度和中度智障成年人进行了为期 3-5 年的心理状态整体变化以及听觉和视觉记忆的特定变化的检查。将 28 名年龄在 27 岁至 55 岁之间患有唐氏综合症 (DS) 的受试者与 18 名智商和年龄相似的无唐氏综合症受试者进行了比较。精神状态的评估包括测试对人、地点和时间的定向、物体命名、视觉运动协调和注意力。听觉记忆是通过 Buschke 记忆测试的改编版本进行测试的。视觉记忆测试包括匹配形状，这些形状在计算机控制的屏幕上同时呈现并在延迟 0、5 和 10 秒后呈现。在最初的测试和长达 5 年后的后续测试之间，没有发现测试分数发生变化，这表明衰老过程并未对这些受试者的认知功能产生重大影响。此外，没有任何迹象表明患有 DS 的老年受试者出现任何表现出痴呆早期症状的普遍下降。
Mildly and moderately mentally retarded adults, who live in the community, were examined for global changes in mental status and specific changes in auditory and visual memory over a period of 3–5 years. Twenty‐eight subjects with Down's syndrome (DS) between the ages of 27 arid 55 years were compared to 18 subjects without DS who were of similar IQ and age. The evaluation of mental status consisted of testing orientation to person, place and time, object naming, visuomotor coordination, and concentration. Auditory memory was tested with an adapted version of the Buschke Memory test. Visual memory testing consisted of matching shapes which were presented simultaneously and after delays of 0, 5 and 10s on a computer‐controlled screen. No changes were found in test scores between an initial testing and follow‐up testing up to 5 years later, indicating that ageing processes were not having a major impact in the cognitive functioning of these subjects. Furthermore, there was no indication of any generalized decline in performance suggestive of early symptoms of dementia among the older subjects with DS.