Reduction of Venom Alkaloids in Solenopsis richteri x Solenopsis invicta Hybrid: An Attempt To Identify New Alkaloidal Components
Reduction of Venom Alkaloids in Solenopsis richteri x Solenopsis invicta Hybrid: An Attempt To Identify New Alkaloidal Components
复制标题
减少红火蚁 x Invicta 杂种红火蚁中毒液生物碱的含量：鉴定新生物碱成分的尝试
DOI：
10.1021/jf103402f
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发表时间：
2010-11-24
影响因子：
6.1
通讯作者：
Fadamiro, Henry Y.
中科院分区：
文献类型：
--
作者：
Chen, Li;Hu, Qiong-Bo;Fadamiro, Henry Y.
采用硅胶色谱和GC-MS技术研究了红火蚁（Solenopsis richteri x Solenopsis invicta）毒液中的生物碱化学。除了亲本种的大多数顺式生物碱外，S. richteri Forel和S. invicta Buren，杂交火蚁体提取物的顺式生物碱级分也含有五种重要的新生物碱。顺式生物碱部分的氢化仅产生5个哌啶，4 '，12'，12，20 '和20。硼氢化钠和氢化铝锂选择性地还原哌啶生物碱中的C=N双键，得到顺式和反式哌啶的混合物。然而，五种新组分的还原产生了几个保留时间更长且分子量增加超过30的新峰。很明显，这五个新峰的化学身份与在红火蚁中发现的已知哌啶或哌啶类化合物有很大不同。
The alkaloid chemistry of the venom of hybrid fire ant, Solenopsis richteri x Solenopsis invicta, was investigated using silica gel chromatography and GC-MS techniques. In addition to most cis alkaloids of parental species, S. richteri Forel and S. invicta Buren, the cis alkaloid fraction of the body extract of hybrid fire ants also contains five significant new alkaloids. Hydrogenation of the cis alkaloid fraction yielded only five piperidines, 4', 12', 12, 20', and 20. Sodium borohydride and lithium aluminum hydride selectively reduced C=N double bond in piperideine alkaloids to give a mixture of cis and trans piperidines. However, reduction of the five new components yielded several new peaks with much longer retention times and increasing molecular weights over 30. It is evident that the chemical identities of the five new peaks are quite different from those known piperidines or piperideines found in Solenopsis fire ants.