Enamel remineralization potential of arginine-fluoride varnish in a multi-species bacterial pH-cycling model.
Enamel remineralization potential of arginine-fluoride varnish in a multi-species bacterial pH-cycling model.
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DOI：
10.1016/j.jdent.2020.103528
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发表时间：
2021-01-01
影响因子：
4.4
通讯作者：
Yiu, Cynthia Kar Yung
中科院分区：
文献类型：
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作者：
Bijle, Mohammed Nadeem;Abdalla, Mohamed Mahmoud;Yiu, Cynthia Kar Yung
目的：利用多菌种pH循环模型，在模拟临床条件下检测精氨酸-氟化钠(Arg-NaF)涂膜对釉质氟的摄取和再矿化潜能。方法：L精氨酸(1%、2%、4%重量比)。加入5%的氟化钠清漆中。实验组和对照组分别为：1%Arg-NaF组、2%Arg-NaF组、4%Arg-NaF组、NaF组和不处理组。在30块釉质标本(n = 6)上形成人工早期龋样病变。处理后标本在口腔生物膜反应器的人工口腔系统中进行多菌种pH循环72 h。结果：随着氟化钠涂膜中精氨酸浓度的增加，早期龋样病变的釉质氟摄取率显著增加(p
OBJECTIVES: To examine the enamel fluoride uptake and remineralization potential of arginine-fluoride (Arg-NaF) varnishes in a simulated clinical condition using a multi-species bacterial pH-cycling model.METHODS: L-Arginine (at 1 %, 2 %, and 4 % by wt.) was incorporated in a 5 % NaF varnish. Experimental and control groups were: 1 % Arg-NaF; 2 % Arg-NaF; 4 % Arg-NaF; NaF and no treatment. Artificial incipient caries-like lesions were formed on 30 enamel specimen blocks (n = 6). The specimens underwent multi-species bacterial pH-cycling in an artificial mouth system using oral biofilm reactor for 72 h after treatment. The specimens were evaluated for mineral density using micro-CT, Ca/P ratio with SEM-EDX, enamel fluoride uptake (EFU) and plaque fluoride uptake (PFU).RESULTS: Increasing concentrations of Arg in NaF varnish significantly increased the EFU of incipient caries-like lesions (p