Spatial spread and demographic expansion of Lyme borreliosis spirochaetes in Eurasia.
Spatial spread and demographic expansion of Lyme borreliosis spirochaetes in Eurasia.
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莱姆疏螺旋体螺旋体在欧亚大陆的空间传播和人口扩张。
DOI：
10.1016/j.meegid.2012.11.014
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发表时间：
2013
期刊：
影响因子：
--
通讯作者：
Margos,Gabriele
中科院分区：
文献类型：
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作者：
Vollmer,StephanieA;Feil,EdwardJ;Chu,Chen-Yi;Raper,StephenL;Cao,Wu-Chun;Kurtenbach,Klaus;Margos,Gabriele
莱姆病螺旋体（LB）组目前包括18个命名的物种，其地理分布，宿主特异性和在人类中引起疾病的能力各不相同。在欧洲有三个种类最为丰富，即阿氏疏螺旋体、伽氏疏螺旋体和瓦氏疏螺旋体，但其中只有两种（B. garinii和B.在亚洲也经常发现。最近发表的一项研究表明，与鸟类有关的疏螺旋体物种，如B。garinii，在欧洲国家之间表现出有限的地理结构，而啮齿动物相关种，B. afzelii，在欧洲表现出广泛的空间结构。在这里，我们使用多位点序列分析表明，当更广泛的，洲际，分布被认为是，有证据表明，即使在鸟类相关的物种B的空间结构。加里尼。此外，我们对历史LB种群的调查为B的范围扩展提供了证据。garinii和B.在遥远的过去，欧洲的阿夫泽利人。我们提出了B.在欧洲的afzelii可能与最后一次盛冰期后啮齿动物种群的扩张有关。
The Lyme borreliosis (LB) group of spirochaetes currently comprises 18 named species that vary in their geographic distribution, host specificity and ability to cause disease in humans. In Europe three species are most abundant, Borrelia afzelii, Borrelia garinii and Borrelia valaisiana but only two of these (B. garinii and B. afzelii) are regularly found in Asia as well. A recently published study has shown that Borrelia species associated with birds, such as B. garinii, showed limited geographic structuring between European countries while, the rodent associated species, B. afzelii, showed extensive spatial structuring in Europe. Here, we use multilocus sequence analysis to show that when the wider, inter-continental, distribution is considered, there is evidence of spatial structuring even in the bird-associated species B. garinii. Furthermore, our investigations into historical LB populations provided evidence for range expansions of B. garinii and B. afzelii populations in Europe in the distant past. We propose that the expansion of B. afzelii in Europe may be linked to rodent population expansions after the last glacial maximum.