Neurocognitive predictors of source monitoring in schizophrenia.
Neurocognitive predictors of source monitoring in schizophrenia.
复制标题
精神分裂症源监测的神经认知预测因子。
DOI：
10.1016/j.psychres.2012.06.014
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发表时间：
2012
影响因子：
11.3
通讯作者：
Docherty,NancyMarsh
中科院分区：
文献类型：
--
作者：
Shakeel,MohammedKalathil;Docherty,NancyMarsh
来源监控（SM）是一个元认知过程，通过招募认知过程来判断信息的来源。SM缺陷与精神分裂症的阳性症状有关。我们调查了精神分裂症患者的某些神经认知功能--特别是注意力、工作记忆和组织排序--是否与SM相关。（听觉连续表现测试），组织排序（连线测验B-A），工作记忆（数字向后），对45例门诊诊断为精神分裂症或情感性精神障碍的患者进行了注意和内部SM的评定，工作记忆和组织排序共同预测SM。组织排序是唯一显着的个人预测，更好的组织排序能力与更好的SM。分层回归分析表明，工作记忆本身并没有导致一个显着的SM预测模型，但增加组织排序导致了一个显着的变化，从工作记忆模型，并导致一个显着的整体模型，占26%的变异SM。结论神经认知功能与SM精神分裂症。组织排序，这需要意识到自我产生的行动，预测SM性能，即使在控制工作记忆。
RATIONALESource monitoring (SM) is a metacognitive process involved in making judgments about the origin of information by recruiting cognitive processes. Deficits in SM have been linked to positive symptoms of schizophrenia. We investigated whether certain neurocognitive functions – specifically attention, working memory, and organizational sequencing – were associated with SM in a sample of schizophrenia patients.METHODSAttention (Auditory Continuous Performance Test), organizational sequencing (Trail-Making Test B–A), working memory (Digits Backward), and internal SM were assessed in 45 outpatients diagnosed with schizophrenia or schizoaffective disorder.RESULTSStandard multiple regression analysis showed attention, working memory and organizational sequencing together predicted SM. Organizational sequencing was the only significant individual predictor, with better organizational sequencing ability being associated with better SM. Hierarchical regression analysis showed that working memory by itself did not result in a significant predictive model of SM, but adding organizational sequencing led to a significant change from the working memory model and resulted in a significant overall model, accounting for 26% of the variance in SM.CONCLUSIONSNeurocognitive functions were associated with SM in schizophrenia. Organizational sequencing, which requires an awareness of self-generated actions, predicted SM performance even after controlling for working memory.