Determinants of major cardiovascular risk factors among participants of the South Carolina WISEWOMAN program, 2009-2012.
Determinants of major cardiovascular risk factors among participants of the South Carolina WISEWOMAN program, 2009-2012.
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DOI：
10.5888/pcd11.140044
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发表时间：
2014-09-04
影响因子：
5.5
通讯作者：
Merchant AT
中科院分区：
文献类型：
--
作者：
Nahhas GJ;Daguise V;Ortaglia A;Merchant AT
心血管疾病（CVD）是美国女性死亡的主要原因，占该人群所有死亡的25%。这些死亡中约65%发生在无症状妇女中。高血压、高胆固醇血症和糖尿病（糖尿病）是CVD的主要危险因素，如果在早期发现，可以有效治疗。数据来自3，572名年龄在40至65岁之间的首次无保险女性参与者，由其健康专业人员转介到南卡罗来纳州全国妇女综合筛查和评估（SC WISEWOMAN），2009-2012年。所有女性都完成了一份结构化的健康风险和行为问卷。记录人体测量指标，并收集临床风险因素数据。通过预测性多变量对数线性模型获得患病率（PR）。未控制的高血压、高胆固醇血症和糖尿病的危险因素患病率分别为34.7%、9.3%和21%。未经治疗的高血压患病率为15.6%;高胆固醇血症为8%;糖尿病为4%。高胆固醇血症的最大显著预测因子是高血压（PR = 4.37），反之亦然（PR = 2.39）。糖尿病最显著的预测因子是肥胖（PR = 2.23）、糖尿病家族史（PR = 2.02）和高胆固醇血症（PR = 1.85）。肥胖（PR = 1.36）、超重（PR = 1.23）、年龄≥ 60岁（PR = 1.26）和黑人（PR = 1.14）是至少有一个CVD危险因素的重要预测因素。黑人（PR = 1.09）是有共病的唯一显著预测因素。在SC WISEWOMAN计划的参与者中，未控制的CVD危险因素的患病率很高。这些研究结果证实，该计划正在接触需要干预措施的高风险妇女，以通过改变生活方式来降低CVD风险。
Cardiovascular disease (CVD) is the leading cause of death among US women, accounting for 25% of all deaths in this population. Approximately 65% of these deaths occur in asymptomatic women. Hypertension, hypercholesterolemia, and diabetes mellitus (diabetes) are major risk factors for CVD and can be treated effectively if identified at an early stage. Data were available from 3,572 uninsured first-time female participants aged 40 to 65 years, referred by their health professional to the South Carolina Well-Integrated Screening and Evaluation for Women Across the Nation (SC WISEWOMAN), 2009–2012. All women completed a structured health-risk and behavior questionnaire. Anthropometric measures were recorded and data on clinical risk-factors were collected. Prevalence-ratios (PRs) were obtained by predictive multivariable log-linear modeling. The prevalence of risk factors was 34.7% for uncontrolled hypertension, 9.3% for hypercholesterolemia, and 21% for diabetes. Prevalence of untreated hypertension was 15.6%; hypercholesterolemia, 8%; and diabetes, 4%. The greatest significant predictor of hypercholesterolemia was hypertension (PR = 4.37) and vice versa (PR = 2.39). The greatest significant predictors of diabetes were obesity (PR = 2.23), family history of diabetes (PR = 2.02), and hypercholesterolemia (PR = 1.85). Being obese (PR = 1.36), overweight (PR = 1.23), aged 60 years or more (PR = 1.26), and black (PR = 1.14) were significant predictors of having at least one CVD risk factor. Being black (PR = 1.09) was the only significant predictor of having comorbid conditions. Prevalence of uncontrolled CVD risk factors was high among participants in the SC WISEWOMAN program. These findings confirm that the program is reaching high-risk women who are in need of interventions to reduce their risk for CVD through lifestyle changes.
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