Combined T2 -preparation and multidimensional outer volume suppression for coronary artery imaging with 3D cones trajectories.
Combined T2 -preparation and multidimensional outer volume suppression for coronary artery imaging with 3D cones trajectories.
复制标题
结合 T2 准备和多维外体积抑制，用于具有 3D 锥体轨迹的冠状动脉成像。
DOI：
10.1002/mrm.28057
复制
发表时间：
2020
影响因子：
3.3
通讯作者：
Nishimura,DwightG
中科院分区：
文献类型：
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作者：
Zeng,DavidY;Baron,CoreyA;Malavé,MarioO;Kerr,AdamB;Yang,PhillipC;Hu,BobS;Nishimura,DwightG
目的：为冠状动脉成像的T2 -制备和多维外容积抑制（OVS）联合开发模块化的磁化制备序列。方法结合T2制备的具有脂肪饱和的1D OVS序列，定义为包含一个90°- 60180°60复合非选择性尖端向下脉冲，两个180°Yhard脉冲用于再聚焦，以及一个- 90°光谱空间自尖端向上脉冲。对于2D OVS，将2个模块连接起来，先选择X，然后选择y。Bloch模拟预测了该序列对b0和b1不均匀性的鲁棒性。将所提出的序列与Luo等人提出的T2制备的2D OVS序列进行比较，后者使用空间选择性的2D螺旋顶端向上。这两个序列在幻影研究和三维锥体轨迹的活体冠状动脉成像研究中进行比较。结果实验结果表明，该序列的OVS优于Luo序列。在对15名健康志愿者的研究中，与Luo序列相比，该序列在右冠状动脉（P< 0.05）和左冠状动脉（P< 0.05）的图像边缘轮廓锐度值更高，表明血管锐度更高。该序列还具有优越的信噪比（P< 0.05）和通阻比（P< 0.05）。阅读器评分和阅读器偏好表明，所提出的序列对右冠状动脉（P< 0.05）和左冠状动脉（P< 0.05）具有优越的冠状动脉图像质量。结论与具有二维空间选择性tip - up的Luo序列相比，该序列具有串联的一维空间选择性tip - up和综合脂肪饱和度，具有更好的图像质量和抑制效果。
PurposeTo develop a modular magnetization preparation sequence for combined T2‐preparation and multidimensional outer volume suppression (OVS) for coronary artery imaging.MethodsA combined T2‐prepared 1D OVS sequence with fat saturation was defined to contain a 90°−60180°60composite nonselective tip‐down pulse, two 180°Yhard pulses for refocusing, and a −90° spectral‐spatial sinc tip‐up pulse. For 2D OVS, 2 modules were concatenated, selective in X and then Y. Bloch simulations predicted robustness of the sequence to B0and B1inhomogeneities. The proposed sequence was compared with a T2‐prepared 2D OVS sequence proposed by Luo et al, which uses a spatially selective 2D spiral tip‐up. The 2 sequences were compared in phantom studies and in vivo coronary artery imaging studies with a 3D cones trajectory.ResultsPhantom results demonstrated superior OVS for the proposed sequence compared with the Luo sequence. In studies on 15 healthy volunteers, the proposed sequence had superior image edge profile acutance values compared with the Luo sequence for the right (P< .05) and left (P< .05) coronary arteries, suggesting superior vessel sharpness. The proposed sequence also had superior signal‐to‐noise ratio (P< .05) and passband‐to‐stopband ratio (P< .05). Reader scores and reader preference indicated superior coronary image quality of the proposed sequence for both the right (P< .05) and left (P< .05) coronary arteries.ConclusionThe proposed sequence with concatenated 1D spatially selective tip‐ups and integrated fat saturation has superior image quality and suppression compared with the Luo sequence with 2D spatially selective tip‐up.