Adjustable Chiral Self-sorting and Self-discriminating Behaviour between Diamond-like Tröger’s Base-linked Cryptands
Adjustable Chiral Self-sorting and Self-discriminating Behaviour between Diamond-like Tröger’s Base-linked Cryptands
复制标题
类金刚石 Tröger 碱基连接的穴状配体之间可调节的手性自排序和自辨别行为
DOI：
10.1039/c9cc03577j
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
Leyong Wang
中科院分区：
文献类型：
--
作者：
Yuan Chen;Cheng Qian;Qian Zhao;Ming Cheng;Xinran Dong;Yue Zhao;Juli Jiang;Leyong Wang
合成了Tröger碱连接的穴状配体5a和5 b的两个异构体，它们都具有两个手性N-中心，表现出罕见的金刚石样支架。特别地，当从rac-5a的溶液中生长时，在晶胞中发现单一对映体RNRN-5a，揭示了手性自分选行为。然而，当加入CF 3COOH质子化Tröger碱在溶液中的rac-5a，两个对映体都形成了对在晶胞中，表现出手性自歧视行为。
Two isomers of Tröger's base-linked cryptands 5a and 5b were synthesized, and both of them have two chiral N-centers, exhibiting rare diamond-like scaffolds. Particularly, when growing from the solution of rac-5a, a single enantiomer RNRN-5a was found in the crystal cell, revealing chiral self-sorting behaviour. However, when adding CF3COOH to protonate Tröger's base in the solution of rac-5a, two enantiomers were both formed in pairs in the crystal cell, exhibiting chiral self-discriminating behaviour.