Aromatic DNA adducts in white blood cells of coke workers.
Aromatic DNA adducts in white blood cells of coke workers.
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焦炭工人白细胞中的芳香族 DNA 加合物。
DOI：
10.1007/bf00379065
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发表时间：
1990
影响因子：
3
通讯作者：
Hewer,A
中科院分区：
文献类型：
--
作者：
Hemminki,K;Grzybowska,E;Chorazy,M;Twardowska-Saucha,K;Sroczynski,JW;Putman,KL;Randerath,K;Phillips,DH;Hewer,A
使用32 P后标记技术测量了焦炭工人、当地对照和农村对照的白色血细胞DNA加合物。该方法检测的芳香族加合物，包括那些形成的多环芳烃（PAHs）。焦炭工人严重暴露于多环芳烃，特别是在电池工作时。加合物水平的差异，注意到在电池的焦炭工人相比，其他工作。非电池组加合物水平高于农村对照组。
White blood cell DNA adducts were measured in coke workers, local controls and countryside controls using the32P-postlabelling technique. The method detected aromatic adducts including those formed by polycyclic aromatic hydrocarbons (PAHs). Coke workers are heavily exposed to PAHs particularly when working at the batteries. A difference in adduct levels was noted between the coke workers at the battery as compared to other jobs. The adduct levels in the non-battery were higher than those in the countryside controls.