ROLE OF SOMATIC AFFERENTS IN AUTONOMIC SYSTEM CONTROL OF THE INTESTINAL MOTILITY
ROLE OF SOMATIC AFFERENTS IN AUTONOMIC SYSTEM CONTROL OF THE INTESTINAL MOTILITY
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DOI：
10.1016/0006-8993(80)90832-x
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发表时间：
1980-01-01
期刊：
影响因子：
2.9
通讯作者：
TERUI, N
中科院分区：
文献类型：
--
作者：
KOIZUMI, K;SATO, A;TERUI, N
在麻醉（氯醛糖-氨基甲酸乙酯）大鼠中，施加于腹部皮肤的强机械刺激总是抑制小肠的运动。这种反射被称为抑制性皮肠反射。类似的刺激施加到上胸部，颈部，前爪或后爪的皮肤引起相反的效果，称为促进皮肠反射。记录小肠传出交感神经的活动和横切肠交感神经或副交感神经表明，抑制性皮肠反射主要是由于肠交感传出神经活动的增加，而易化性皮肠反射是由于肠交感传出神经活动的减少;这两种变化都是反射诱发的。抑制性皮肠反射是由第IV组（无髓）皮肤传入神经纤维兴奋引起的脊髓本体反射。易化性皮肠反射似乎是通过脊髓上通路介导的，并且主要由第III组（A-delta组）皮肤传入神经纤维的兴奋引起。证明了皮肠反射和肌肠反射之间的相互作用。排除了背根反射对皮肠反射的影响。本文还讨论了皮肠反射在胃肠道神经控制中的意义。
In anesthetized (chloralose-urethane) rats, strong mechanical stimuli which were applied to the abdominal skin always inhibited motility of the small intestine. This reflex is referred to as an inhibitory cutaneo-intestinal reflex. Similar stimuli applied to the skin of the upper chest, neck, forepaws or hindpaws evoked the opposite effect, referred to as a facilitatory cutaneo-intestinal reflex. Recording the activity of efferent sympathetic nerves to the small intestine and transecting intestinal sympathetic or parasympathetic nerves showed that the inhibitory cutaneo-intestinal reflex was largely due to an increase in intestinal sympathetic efferent activity, and that the facilitatory cutaneo-intestinal reflex was due to a decrease in the intestinal sympathetic efferent nerve activity; both changes reflexly evoked. The inhibitory cutaneo-intestinal reflex was a propriospinal reflex caused by excitation of group IV (unmyelinated) cutaneous afferent nerve fibers. The facilitatory cutaneo-intestinal reflex seemed to be mediated through supraspinal pathways, and was evoked by excitation of mainly group III (A-delta group) cutaneous afferent nerve fibers. Interaction between the cutaneo-intestinal reflex and intestino-intestinal reflex was demonstrated. The possibility of a dorsal root reflex contribution to cutaneo-intestinal reflex was eliminated. The significance of the cutaneo-intestinal reflex in neural control of the gastrointestinal tract was discussed.