Biosynthesis of the Natural Fluorophore Legioliulin from Legionella
Biosynthesis of the Natural Fluorophore Legioliulin from Legionella
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DOI：
10.1002/cbic.201300373
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发表时间：
2013-08-19
期刊：
影响因子：
3.2
通讯作者：
Bode, Helge B.
中科院分区：
文献类型：
--
作者：
Ahrendt, Tilman;Miltenberger, Melissa;Bode, Helge B.
让它发光吧：研究了军团菌（Legionella sp .）的紫外荧光团军团蛋白(1)的生物合成，并对苯丙氨酸铵裂解酶（lld）进行了生化表征。此外，两个新的衍生物在不同的起动机单位已确定通过突变合成实验。
Let it shine: The biosynthesis of the UV fluorophore legioliulin (1) from Legionella spp. was elucidated and the phenylalanine ammonium lyase LglD responsible for the formation of the starter unit cinnamic acid was biochemically characterized. Additionally, two novel derivatives differing in the starter unit have been identified by mutasynthesis experiments.