Three-dimensional MRI study of the relationship between eye dimensions, retinal shape and myopia
Three-dimensional MRI study of the relationship between eye dimensions, retinal shape and myopia
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DOI：
10.1364/boe.8.002386
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发表时间：
2017-05-01
影响因子：
3.4
通讯作者：
Atchison, David A.
中科院分区：
文献类型：
--
作者：
Pope, James M.;Verkicharla, Pavan K.;Atchison, David A.
我们调查了眼睛尺寸和视网膜形状随近视程度、性别和种族的变化。58例年轻成人正视眼和近视眼（范围-1.25 D至-8.25 D），其中30例东亚人（21例女性/9例男性），23例白人（16/7）和5例南亚人（1/4）。使用3.0特斯拉全身临床MRI系统进行三维磁共振成像，该系统使用位于眼睛上方的4.0 cm仅接收表面线圈。自动化方法确定眼睛的长度，宽度和高度，和曲线拟合程序确定不对称和对称的椭圆体形状的视网膜的75%，55%和35%。随着近视增加，眼睛尺寸在所有方向上增加，使得长度的增加显著大于宽度和高度的增加。正视眼的视网膜呈扁圆形（从顶点开始变陡），但扁圆度随着近视的增加而降低，因此在7至8D近视时视网膜近似为球形。眼睛关于最佳拟合视轴的不对称性通常较小，顶点曲率半径之间以及轴向和矢状面非球面之间的差异较小。女性的眼睛比男性小，前者的整体尺寸约为0.5毫米。种族似乎没有系统的影响。(C)2017美国光学学会
We investigated changes in eye dimensions and retinal shape with degree of myopia, gender and race. There were 58 young adult emmetropes and myopes (range -1.25D to -8.25D), with 30 East-Asians (21 female/9 male), 23 Caucasians (16/7) and 5 South-Asians (1/4). Three-dimensional magnetic resonance imaging was undertaken with a 3.0 Tesla whole-body clinical MRI system using a 4.0 cm receive-only surface coil positioned over the eye. Automated methods determined eye length, width and height, and curve fitting procedures determined asymmetric and symmetric ellipsoid shapes to 75%, 55% and 35% of the retina. With myopia increase, eye dimensions increased in all directions such that increase in length was considerably greater than increases in width and height. Emmetropic retinas were oblate (steepening away from the vertex) but oblateness decreased with the increase in myopia, so that retinas were approximately spherical at 7 to 8D myopia. Asymmetry of eyes about the best fit visual axis was generally small, with small differences between the vertex radii of curvature and between asphericities in the axial and sagittal planes. Females had smaller eyes than males, with overall dimensions being about 0.5mm less for the former. Race appeared not to have a systematic effect. (C) 2017 Optical Society of America