Risk factors of infant anemia in the perinatal period
Risk factors of infant anemia in the perinatal period
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DOI：
10.1111/ped.13174
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发表时间：
2017-04-01
影响因子：
1.4
通讯作者：
Yoda, Hitoshi
中科院分区：
文献类型：
--
作者：
Hirata, Michio;Kusakawa, Isao;Yoda, Hitoshi
研究背景婴儿尤其易患缺铁性贫血。我们调查的母亲和婴儿的血细胞计数的变化，以及它们之间的关系和婴儿营养方法和婴儿anemia.MethodsThis回顾性队列研究包括健康的新生儿出生于2011年8月至2014年7月在圣卢克国际医院，东京，日本之间的关系。分析了妊娠晚期获得的母亲血液样本和出生时以及3、6和9个月大的婴儿血液样本的数据。使用多变量Logistic回归，我们调查了营养方法，母亲贫血，和其他临床相关参数，是潜在的危险因素为infant anemia.ResultsIn total，数据为3472婴儿和他们的母亲进行了分析。营养方式是婴儿贫血最重要的危险因素，未来贫血的风险依次为：纯母乳喂养，部分母乳喂养，配方奶粉喂养。此外，低脐带血血红蛋白导致贫血的倾向在child.ConclusionInfant营养方法是最显着的因素有关的贫血在婴儿后期。脐带血血红蛋白低的婴儿在婴儿后期更容易患贫血。
BackgroundInfants are at particular risk of iron-deficiency anemia. We investigated changes in the blood count of the mother and infant as well as the relationship between them and the relationship between infant nutrition method and infant anemia.MethodsThis retrospective cohort study included healthy neonates born between August 2011 and July 2014 at St Luke's International Hospital, Tokyo, Japan. Data from maternal blood samples obtained during late pregnancy and those of infants obtained at birth and at the age of 3, 6, and 9 months were analyzed. Using multivariate logistic regression, we investigated nutrition methods, maternal anemia, and other clinically relevant parameters that were potential risk factors for infant anemia.ResultsIn total, data for 3472 infants and their mothers were analyzed. Nutrition method was the most significant risk factor for infant anemia, with risk of future anemia decreasing in the following order: exclusive breast-feeding, partial breast-feeding, and formula feeding. Furthermore, low umbilical cord blood hemoglobin led to a tendency toward anemia in the child.ConclusionInfant nutrition method was the most significant factor related to anemia in late infancy. Infants with low umbilical cord blood hemoglobin are more likely to develop anemia in late infancy.