Response shift due to diagnosis and primary treatment of localized prostate cancer: a then-test and a vignette study.
Response shift due to diagnosis and primary treatment of localized prostate cancer: a then-test and a vignette study.
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DOI：
10.1007/s11136-007-9265-6
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发表时间：
2007-12
影响因子：
3.5
通讯作者：
Essink-Bot, Marie-Louise
中科院分区：
文献类型：
--
作者：
Korfage, Ida J.;de Koning, Harry J.;Essink-Bot, Marie-Louise
到目前为止，前列腺癌诊断是否会引起反应转变尚未确定。因此，我们评估了被诊断患有局限性前列腺癌的男性的反应变化。在筛查前完成问卷调查的3，892名男性中，有82人随后被诊断患有前列腺癌。通过当时的测试（EuroQol健康自评，Short-Form 36心理健康和活力）和一种新方法评估了52名患者（响应63%）的响应变化：与前列腺癌治疗副作用（泌尿，肠道和勃起功能障碍）相关的小插曲评级。进行了三次然后测试：两次参考诊断前（治疗前和治疗后测量），一次参考治疗前（治疗后测量）。诊断前的健康测试分数显着高于原始分数，表明在回顾时更积极的判断。治疗前健康状况的测试分数低于最初的分数。特别是勃起功能障碍的小插曲在诊断后比诊断前被评为不那么糟糕（P <0.001，中等效应量）。我们在被诊断为前列腺癌的男性中发现了反应转变的证据。男性在成为预期会经历这些副作用的患者后，对泌尿、肠道和勃起功能障碍的评估结果不那么糟糕。小插曲的评级是一个有前途的额外的技术，以评估反应的转变。
Whether a prostate cancer diagnosis induces response shift has not been established so far. Therefore, we assessed response shift in men who were diagnosed with localized prostate cancer. Out of 3,892 men who completed a questionnaire before screening, 82 were subsequently diagnosed with prostate cancer. Response shift was assessed in 52 (response 63%) by the then-test (EuroQol self-rating of health, Short-Form 36 mental health and vitality) and a novel method: rating of vignettes relating to side effects of prostate cancer treatment (urinary, bowel and erectile dysfunction). Three then-tests were conducted: two referencing pre-diagnosis (measured pre- and post-treatment), and one referencing pre-treatment (measured post-treatment). Then-test scores of pre-diagnosis health were significantly higher than original scores, indicating a more positive judgement in retrospect. Then-test scores of pre-treatment health were lower than original scores. Especially the vignette on erectile dysfunction was rated less bad after diagnosis versus before (P < 0.001, moderate effect size). We found evidence for response shift in men who were diagnosed with prostate cancer. Men evaluated urinary, bowel, and erectile dysfunction as less bad after they had become patients who can expect to experience these side effects. The rating of vignettes is a promising additional technique to assess response shift.
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影响因子：
3.3
作者：
Brooks, R
通讯作者：
Brooks, R
影响因子：
5.4
作者：
Korfage, Ida Joanna;Hak, Tony;Essink-Bot, Marie-Louise
通讯作者：
Essink-Bot, Marie-Louise
影响因子：
8.4
作者：
Korfage, IJ;de Koning, HJ;Essink-Bot, ML
通讯作者：
Essink-Bot, ML
DOI：
10.3816/cgc.2005.n.007
发表时间：
2005-06-01
期刊：
Clinical prostate cancer
影响因子：
--
作者：
Kramer, Karen M;Bennett, Charles L;Knight, Sara J
通讯作者：
Knight, Sara J
影响因子：
4.5
作者：
Roobol, MJ;Kirkels, WJ;Schröder, FH
通讯作者：
Schröder, FH