Prevalence and Risk Factors of Lower Reproductive Tract Infections in Symptomatic Women in Dakar, Senegal.
Prevalence and Risk Factors of Lower Reproductive Tract Infections in Symptomatic Women in Dakar, Senegal.
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DOI：
10.1177/1178633719851825
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发表时间：
2019-01-01
影响因子：
5.8
通讯作者：
Moreau, Jean Charles
中科院分区：
文献类型：
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作者：
Diadhiou, Mohamed;Ba Diallo, Awa;Moreau, Jean Charles
背景：女性下生殖道感染是发病率的重要原因，但也可导致并发症和后遗症。本研究旨在确定达喀尔（塞内加尔）育龄妇女下生殖道感染的患病率和危险因素。方法：采用前瞻性研究方法，于2015年7 - 11月在6家妇产医院开展。参与者的年龄从18岁到49岁不等，在卫生机构出现生殖器感染的体征和症状。本研究招募了符合纳入标准的同意个体。结果：在报告期内，共有276例患者入组。根据实验室结果，任何生殖器感染的患病率为69.6%（276人中有192人）。最常见的阴道感染是细菌性阴道病（39.5%）和阴道念珠菌病（29%），第三个最常见的原因是滴虫病，在患病率方面落后（2.5%）。在导致宫颈感染的微生物中，解脲原体最多（27.5%），其次是人支原体（14.5%）、沙眼衣原体（4.7%）和淋病奈瑟菌（1.1%）。多因素分析显示，年轻妇女和受教育程度低的妇女阴道/宫颈感染的风险增加。结论：本研究揭示了细菌性阴道病和阴道念珠菌病的高患病率，并建议卫生保健提供者应提高认识和沟通，以改善阴道卫生习惯。如果怀疑感染阴道毛滴虫、沙眼衣原体或淋病奈瑟菌，我们还建议系统地进行实验室诊断确认。
BACKGROUND: Lower reproductive tract infections in women are important causes of morbidity but can also lead to complications and sequelae. This study aimed to establish the prevalence and risk factors of lower genital tract infections among women of reproductive age in Dakar (Senegal).METHODS: This was a prospective study conducted in 6 maternity hospitals from July to November 2015. Participants ranged in age from 18 to 49years and presented at health facilities with signs and symptoms of genital infection. Consenting individuals who met the inclusion criteria were recruited for the study.RESULTS: During the reporting period, 276 patients were enrolled. According to the laboratory results, the prevalence of any genital infection was 69.6% (192 of 276). The most common vaginal infections were bacterial vaginosis (39.5%) and vaginal candidiasis (29%), with the third most common cause, trichomoniasis, trailing behind in terms of prevalence (2.5%). Among the microorganisms responsible for cervical infections, Ureaplasma urealyticum was the most frequent (27.5%), followed by Mycoplasma hominis (14.5%), Chlamydia trachomatis (4.7%), and Neisseria gonorrhoeae (1.1%). Multivariate analysis showed that young women and women with low levels of education were at increased risk for vaginal/cervical infections.CONCLUSIONS: This study revealed a high prevalence of bacterial vaginosis and vaginal candidiasis and suggests that health care providers should increase awareness and communication to improve vaginal hygiene practices. If infection with Trichomonas vaginalis, C trachomatis or N gonorrhoeae is suspected, we also recommend systematically performing laboratory diagnostic confirmation.