STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology STROBE-ME: an extension of the STROBE statement
STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology STROBE-ME: an extension of the STROBE statement
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DOI：
10.1016/j.jclinepi.2011.07.010
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发表时间：
2011-12-01
影响因子：
7.2
通讯作者：
Vineis, Paolo
中科院分区：
文献类型：
--
作者：
Gallo, Valentina;Egger, Matthias;Vineis, Paolo
实验室技术的进步导致生物标志物在流行病学研究中的使用迅速增加。内部剂量的生物标志物、早期生物变化敏感性和临床结果被用作研究外部和/或内源性因素与身体成分或过程之间相互作用的代理。改进科学研究报告的需要导致了有影响力的建议声明，例如加强流行病学观察研究报告 (STROBE) 声明。 STROBE 倡议成立于 2004 年，旨在为如何报告观察性研究提供指导。其指南提供了一份用户友好的清单，其中包含流行病学研究中要报告的 22 个项目，其中项目特定于三种主要研究设计：队列研究、病例对照研究和横断面研究。目前的加强流行病学观察研究报告 - 分子流行病学 (STROBE-ME) 计划以 STROBE 声明为基础，实施了 9 个现有的 STROBE 项目，并在 STROBE 检查表的 22 个项目的基础上增加了 17 个项目。新增内容涉及流行病学研究中生物标志物的使用，涉及生物样本的收集、处理和储存；实验室方法、生物标志物的有效性和可靠性；研究设计的特殊性；和道德考虑。 STROBE-ME 建议旨在补充 STROBE 建议。 (C) 2011 作者。版权所有。
Advances in laboratory techniques have led to a rapidly increasing use of biomarkers in epidemiological studies. Biomarkers of internal dose, early biological change susceptibility and clinical outcomes are used as proxies for investigating the interactions between external and/or endogenous agents and body components or processes. The need for improved reporting of scientific research led to influential statements of recommendations such as the STrengthening Reporting of OBservational studies in Epidemiology (STROBE) statement. The STROBE initiative established in 2004 aimed to provide guidance on how to report observational research. Its guidelines provide a user-friendly checklist of 22 items to be reported in epidemiological studies, with items specific to the three main study designs: cohort studies, case-control studies and cross-sectional studies. The present STrengthening the Reporting of OBservational studies in Epidemiology - Molecular Epidemiology (STROBE-ME) initiative builds on the STROBE statement implementing 9 existing items of STROBE and providing 17 additional items to the 22 items of STROBE checklist. The additions relate to the use of biomarkers in epidemiological studies, concerning collection, handling and storage of biological samples; laboratory methods, validity and reliability of biomarkers; specificities of study design; and ethical considerations. The STROBE-ME recommendations are intended to complement the STROBE recommendations. (C) 2011 The Authors. All rights reserved.