Dual energy X-ray absorptiometry produces larger measurement error in non-Hispanic Caucasians than Hispanics.
Dual energy X-ray absorptiometry produces larger measurement error in non-Hispanic Caucasians than Hispanics.
复制标题
双能 X 射线吸收测定法在非西班牙裔白种人中产生的测量误差比西班牙裔人更大。
DOI：
10.1016/j.clnesp.2022.12.012
复制
发表时间：
2023
影响因子：
3
通讯作者：
Esco,MichaelR
中科院分区：
文献类型：
--
作者：
Nickerson,BrettS;Cicone,ZackaryS;Park,Kyung-Shin;Snarr,RonaldL;Fedewa,MichaelV;Esco,MichaelR
背景双能 X 射线吸收测定法 (DXA) 通常用作身体成分研究和临床环境中估计身体脂肪百分比 (%Fat) 的标准测量。 DXA 预测脂肪百分比的准确性主要在非西班牙裔人群中进行。目的本研究的目的是确定 DXA 衍生的脂肪百分比在西班牙裔和非西班牙裔白种人成人中的一致性。方法样本由西班牙裔男性 (n = 96) 和女性 (n = 102) 以及非西班牙裔白种人男性组成（n = 145）和女性（n = 161）。通过恒定误差（CE = DXA – 4C 模型）和 95% 的一致性限度，将全身 DXA 扫描的脂肪百分比与标准 4 室 (4C) 模型进行比较。此外，还使用 CE 作为因变量进行 2 × 2 阶乘方差分析，以检验性别和种族的主要影响和交互影响。结果与 4C 模型相比，DXA 高估了西班牙裔白人的脂肪百分比 4.0%，高估了非西班牙裔白种人的 5.5%（所有 p < 0.05）。所有组比较的 95% 一致限度范围为 ±5.5% 至 ±5.9%。 2 × 2 阶乘方差分析表明，非西班牙裔白种人的 CE 高于西班牙裔（CE 差异 = 1.5%；p < 0.05）。结论我们的研究结果显示，与 4C 模型相比，无论性别（男性或女性），DXA 显着高估了两个人群（西班牙裔和非西班牙裔白种人）的脂肪百分比。然而，这种错误在非西班牙裔白人成年人中更为严重。 DXA 对于追踪生活方式干预过程中发生的身体成分变化可能很有用，这一点毫无价值。尽管如此，从业者应该意识到，DXA 估计的脂肪百分比可能大于 4C 模型获得的实际值。
BackgroundDual energy X-ray absorptiometry (DXA) is often used as a criterion measure in body composition research and in clinical settings for the estimate of body fat percent (%Fat). The accuracy of DXA for predicting %Fat has primarily been conducted in non-Hispanic populations.AimThe purpose of this study was to determine the agreement of DXA-derived %Fat in Hispanic and non-Hispanic Caucasian adults.MethodsThe sample consisted of Hispanic males (n = 96) and females (n = 102) and non-Hispanic Caucasian males (n = 145) and females (n = 161). The %Fat of a whole-body DXA scan was compared against a criterion 4-compartment (4C) model via constant error (CE = DXA – 4C model) and 95% limits of agreement. Also, a 2 × 2 factorial ANOVA, using CE as a dependent variable, was conducted to examine the main and interaction effects of sex and ethnicity.ResultsWhen compared to the 4C model, DXA overestimated %Fat by 4.0% in Hispanics and 5.5% in non-Hispanic Caucasians (all p < 0.05). The 95% limits of agreement ranged from ±5.5% to ±5.9% for all group comparisons. The 2 × 2 factorial ANOVA indicated the CE was greater in non-Hispanic Caucasians than Hispanics (CE difference = 1.5%; p < 0.05).ConclusionOur findings revealed that DXA significantly overestimates %Fat in both populations (Hispanics and non-Hispanic Caucasians), when compared to a 4C model, regardless of sex (male or female). However, the error is more profound in non-Hispanic Caucasian adults. It is worth nothing that DXA may be useful for tracking changes in body composition that occur throughout a lifestyle intervention. Nonetheless, practitioners should be aware that the estimate of %Fat from DXA may be larger than the actual values obtained from a 4C model.