Interventions Improve Poor Adherence with Once Daily Glaucoma Medications in Electronically Monitored Patients
Interventions Improve Poor Adherence with Once Daily Glaucoma Medications in Electronically Monitored Patients
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DOI:
10.1016/j.ophtha.2009.05.026
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发表时间:
2009-12-01
期刊:
影响因子:
13.7
通讯作者:
Friedman, David S.
中科院分区:
文献类型:
--
作者:
Okeke, Constance O.;Quigley, Harry A.;Friedman, David S.
Purpose: To investigate the impact of an intervention program to improve adherence with topical, once daily therapy for glaucoma.Design: Randomized controlled clinical trial.Participants: Sixty-six patients with glaucoma being treated with a prostaglandin analog in 1 or both eyes at the Scheie Eye Institute or Wilmer Eye Institute between November 2006 and June 2007.Methods: In an observational study, participants who took 75% or fewer doses (as measured using the travoprost Dosing Aid [DA]) during an initial 3-month period were randomized into 2 groups. The intervention group watched an educational video, reviewed current barriers to drop-taking and possible solutions with a study coordinator, received regular phone call reminders, and had audible and visible reminders activated on their DA devices. The control group was told to take drops as prescribed and received no additional intervention.Main Outcome Measures: Change in drop use adherence as determined by the DA device.Results: In the 3-month observation period before randomization, intervention group patients had used a mean of 54 +/- 17% of scheduled doses, and this increased to 73 +/- 22% during the following 3-month period (P