Acute Large Vessel Ischemic Stroke in Patients With COVID-19-Related Multisystem Inflammatory Syndrome.
Acute Large Vessel Ischemic Stroke in Patients With COVID-19-Related Multisystem Inflammatory Syndrome.
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DOI：
10.1016/j.pediatrneurol.2021.09.013
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发表时间：
2022-01
影响因子：
3.8
通讯作者：
Dafer RM
中科院分区：
文献类型：
--
作者：
Chang J;Bulwa Z;Breit H;Cherian LJ;Conners JJ;Song SY;Dafer RM
急性缺血性中风（AIS）在儿童中很少见，而且诊断常常被延误。儿童多系统炎症综合征（MIS-C）可能发生神经系统受累，但 MIS-C 患者发生 AIS 的病例报道很少。我们的两名 AIS 患者在最近暴露于 SARS-CoV-2 感染的既往健康青少年中出现大血管闭塞性疾病。两名患者随后均被诊断患有 MIS-C 并接受治疗。在这里，我们讨论他们的治疗过程和临床反应。早期识别和诊断 MIS-C 儿童伴大血管闭塞的 AIS 对于提供所有治疗方案以改善临床结果至关重要。
Acute ischemic stroke (AIS) is rare in children, and diagnosis is often delayed. Neurological involvement may occur in multisystem inflammatory syndrome in children (MIS-C), but very few cases of AIS in patients with MIS-C have been reported. We two patients with AIS presenting with large vessel occlusive disease in previously healthy adolescents recently exposed to SARS-CoV-2 infection. Both patients were subsequently diagnosed with and treated for MIS-C. Here, we discuss the course of their treatments and clinical responses. Early recognition and diagnosis of AIS with large vessel occlusion in children with MIS-C is critical to make available all treatment options to improve clinical outcomes.
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影响因子：
4
作者：
Mavrogeni SI;Kolovou G;Tsirimpis V;Kafetzis D;Tsolas G;Fotis L
通讯作者：
Fotis L
影响因子：
11.2
作者：
Beslow, Lauren A.;Linds, Alexandra B.;Dlamini, Nomazulu
通讯作者：
Dlamini, Nomazulu
DOI：
10.1056/nejmoa2102968
发表时间：
2021-07-01
期刊：
The New England journal of medicine
影响因子：
--
作者：
McArdle AJ;Vito O;Patel H;Seaby EG;Shah P;Wilson C;Broderick C;Nijman R;Tremoulet AH;Munblit D;Ulloa-Gutierrez R;Carter MJ;De T;Hoggart C;Whittaker E;Herberg JA;Kaforou M;Cunnington AJ;Levin M;BATS Consortium
通讯作者：
BATS Consortium
影响因子：
19.7
作者：
Mirzaee SMM;Gonçalves FG;Mohammadifard M;Tavakoli SM;Vossough A
通讯作者：
Vossough A
DOI：
10.1016/s2352-4642(20)30314-x
发表时间：
2021-01
期刊：
The Lancet. Child & adolescent health
影响因子：
--
作者：
Tiwari L;Shekhar S;Bansal A;Kumar S
通讯作者：
Kumar S