A class of generalized linear mixed models adjusted for marginal interpretability
A class of generalized linear mixed models adjusted for marginal interpretability
复制标题
一类针对边际可解释性进行调整的广义线性混合模型
DOI:
10.1002/sim.8782
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发表时间:
2020
影响因子:
2
通讯作者:
MacEachern, Steven N.
中科院分区:
文献类型:
--
作者:
Gory, Jeffrey J.;Craigmile, Peter F.;MacEachern, Steven N.
Two popular approaches for relating correlated measurements of a non‐Gaussian response variable to a set of predictors are to fit amarginal modelusing generalized estimating equations and to fit ageneralized linear mixed model(GLMM) by introducing latent random variables. The first approach is effective for parameter estimation, but leaves one without a formal model for the data with which to assess quality of fit or make individual‐level predictions for future observations. The second approach overcomes these deficiencies, but leads to parameter estimates that must be interpreted conditional on the latent variables. To obtain marginal summaries, one needs to evaluate an analytically intractable integral or use attenuation factors as an approximation. Further, we note an unpalatable implication of the standard GLMM. To resolve these issues, we turn to a class of marginally interpretable GLMMs that lead to parameter estimates with a marginal interpretation while maintaining the desirable statistical properties of a conditionally specified model and avoiding problematic implications. We establish the form of these models under the most commonly used link functions and address computational issues. For logistic mixed effects models, we introduce an accurate and efficient method for evaluating the logistic‐normal integral.
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影响因子:
1.9
作者:
STIRATELLI, R;LAIRD, N;WARE, JH
通讯作者:
WARE, JH
影响因子:
2.7
作者:
NEUHAUS, JM;JEWELL, NP
通讯作者:
JEWELL, NP
影响因子:
2.4
作者:
D. Pirjol
通讯作者:
D. Pirjol
DOI:
10.1016/j.jspi.2010.12.021
发表时间:
2011
期刊:
Fuel and Energy Abstracts
影响因子:
--
作者:
Yongdai Kim;Do
通讯作者:
Do
DOI:
10.1093/biostatistics/5.3.381
发表时间:
2004
期刊:
Biostatistics (Oxford, England)
影响因子:
--
作者:
Miglioretti,DianaL;Heagerty,PatrickJ
通讯作者:
Heagerty,PatrickJ