Early Parkinson's disease and non-motor issues
Early Parkinson's disease and non-motor issues
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DOI：
10.1007/s00415-008-5006-1
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发表时间：
2008-09-01
影响因子：
6
通讯作者：
Naidu, Yogini
中科院分区：
文献类型：
--
作者：
Chaudhuri, K. Ray;Naidu, Yogini
帕金森病的非运动症状(NMS)是影响帕金森病患者健康、生活质量和社会成本的重要因素。与通常的看法相反，许多帕金森病的NMS发生在帕金森病的早期，有些甚至可能早于以运动体征为基础的帕金森病的诊断。这些问题包括嗅觉障碍、睡眠问题，如快速眼动行为障碍、便秘以及最近被描述的男性勃起功能障碍。NMSQuest(NMSQuest)和最近验证的NMS量表允许伪造和量化PD的NMS，因此是全面评估PD症状负荷的重要工具。
Non motor symptoms (NMS) of PD are a key determinant of health, quality of life and societal cost of PD. Contrary to common perception, many NMS of PD occur early in PD and some may even predate the diagnosis of PD which is based on motor signs. These include olfactory deficit, sleep problems such as REM behaviour disorder, contipation and the more recently described male erectile dysfunction. The non motor quesionnaire (NMSQuest) and the recently validated NMS scale allow falgging and quantification of NMS of PD and therefore are important tools to comprehensively assess symptom load in PD.