Ischemic tolerance in the brain.

Ischemic tolerance in the brain.
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DOI:
10.1556/aphysiol.92.2005.1.9
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发表时间:
2005-07
影响因子:
--
通讯作者:
KJ Kapinya
KJ Kapinya
中科院分区:
医学4区
文献类型:
--
作者:
KJ Kapinya

文献摘要

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内源性脑缺血耐受是自然界的神经保护策略。探索这种现象的生理和分子机制可能会给我们提供新的手段,防止缺血和其他退行性疾病。本文综述了目前诱导脑缺血耐受的实验方法,并对可能的作用机制进行了简要总结。
Endogenous tolerance to cerebral ischemia is nature's strategy for neuroprotection. Exploring the physiologic and molecular mechanism of this phenomenon may give us new means of protection against ischemia and other degenerative disorders. This article reviews the currently available experimental methods to induce ischemic tolerance in the brain and gives a brief summary of the potential mode of action.