THYROID FUNCTION IN BREAST CANCER
THYROID FUNCTION IN BREAST CANCER
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DOI：
10.1530/acta.0.0510290
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发表时间：
1966-01-01
期刊：
影响因子：
--
通讯作者：
HALES, IB
中科院分区：
文献类型：
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作者：
MYHILL, J;REEVE, TS;HALES, IB
甲状腺放射性碘131清除率测定后1小时静脉注射示踪剂剂量显着高于37例血行转移或在117名正常人的29例乳腺癌患者的局部疾病。13例血行转移瘤患者的化学蛋白结合碘（PBI）明显高于311例正常人。10例有乳腺癌病史但目前无临床或X线影像学证据的患者，其清除率与血液转移患者一致。然而，PBI是正常的。测量24小时摄取、24小时甲状腺外滞留放射性碘、甲状腺放射性碘蓄积曲线、肾放射性碘清除率和血清促甲状腺激素水平，均无显著性发现。
Thyroidal radio-I131 clearance rate measured at 1 hour after intravenous injection of a tracer dose was significantly higher in 29 breast cancer patients with local disease only than in 37 with blood borne metastases or in 117 normal subjects. Chemical protein bound iodine (PBI) was significantly higher in 13 patients with blood borne metastases than in 311 normal subjects. Ten patients with a history of proven breast cancer, but no present clinical or radio-graphic evidence of disease, evidenced a clearance rate consistent with that of patients with blood metastases. The PBI, however, was normal. Measurements were made of 24 hour uptake, extra-thyroidal retained radioiodide at 24 hours, thyroidal radioiodine accumulation curves, renal radioiodine clearance rates and serum thyroid stimulating hormone level, with no significant findings.