Course of fatigue in women receiving chemotherapy and/or radiotherapy for early stage breast cancer
Course of fatigue in women receiving chemotherapy and/or radiotherapy for early stage breast cancer
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DOI：
10.1016/j.jpainsymman.2004.01.012
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发表时间：
2004-10-01
影响因子：
4.7
通讯作者：
McGrath, P
中科院分区：
文献类型：
--
作者：
Donovan, KA;Jacobsen, PB;McGrath, P
虽然已经了解了很多关于乳腺癌治疗期间疲劳的并发症，但尚未确定乳腺癌患者疲劳经历的治疗方式之间存在差异的可能性。在这项研究中，对134名接受化疗和放疗或仅接受早期乳腺癌放疗的妇女进行了疲劳评估。在初始治疗期间的疲劳比较表明，接受化疗的妇女比接受放疗的妇女报告更大的疲劳严重程度皮破坏。未接受化疗预处理的女性在放疗过程中疲劳增加。结果证实了早期乳腺癌女性的疲劳程度随治疗类型和治疗顺序的不同而不同的预测。研究结果表明，在放疗期间疲劳的增加，只有在妇女没有接受化疗预处理，表明反应的转变，或内部标准的变化，在妇女的疲劳作为一个功能的先前化疗治疗的看法。(C)2004年美国癌症疼痛缓解委员会。爱思唯尔公司出版All rights reserved.
Although much has been learned about the complication of fatigue during breast cancer treatment, the possibility that there are differences across treatment modalities in breast cancer patients' experience of fatigue has not yet been established. In this study, fatigue was assessed in 134 women receiving chemotherapy and radiotherapy or radiotherapy only for early stage breast cancer. Comparisons of fatigue during initial treatment indicated that women who received chemotherapy reported greater fatigue severity rind disruptiveness than women receiving radiotherapy. Women not pre-treated with chemotherapy experienced increased fatigue over the course of radiotherapy. Results confirmed predictions that fatigue in women with early stage breast cancer differs as a function of the type of treatment and sequencing of treatment. Findings indicating increases in fatigue during radiotherapy only among women not pretreated with chemotherapy suggest a response shift, or a change in internal standards, in women's perceptions of fatigue as a function of prior chemotherapy treatment. (C) 2004 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.