ASPIRATION OF THE ASYMPTOMATIC METATARSOPHALANGEAL JOINT IN GOUT PATIENTS AND HYPERURICEMIC CONTROLS
ASPIRATION OF THE ASYMPTOMATIC METATARSOPHALANGEAL JOINT IN GOUT PATIENTS AND HYPERURICEMIC CONTROLS
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DOI：
10.1002/art.1780250215
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发表时间：
1982-01-01
影响因子：
--
通讯作者：
HOLMES, EW
中科院分区：
文献类型：
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作者：
ROUAULT, T;CALDWELL, DS;HOLMES, EW
对一组痛风患者、2 个高尿酸血症对照组和 1 个正常尿酸血症对照组进行无症状跖趾关节抽吸。 70%的痛风患者存在细胞外尿酸盐晶体，19名无症状高尿酸血症患者中有1名存在细胞外尿酸盐晶体，9名肾功能衰竭和高尿酸血症但无关节病史的患者中有2名存在细胞外尿酸盐晶体。在 10 名患有其他类型关节炎的正常尿酸血症患者中未发现晶体。痛风受试者中晶体的存在与足底痛病史、痛风持续时间、痛风石的存在或高尿酸血症的控制程度无关。尽管在无症状高尿酸血症受试者的关节液中很少发现晶体，但无症状关节中存在这些晶体在痛风受试者中更为常见。
Asymptomatic metatarsophalangeal joints were aspirated in a group of patients with gout, in 2 control groups with hyperuricemia and in 1 normouricemic control group. Extracellular urate crystals were present in 70% of gout patients, in 1 of 19 patients with asymptomatic hyperuricemia and in 2 of 9 patients with renal failure and hyperuricemia but no history of joint disease. Crystals were not found in the 10 normouricemic patients who had other types of arthritis. The presence of crystals in the subjects with gout was not correlated with a history of podagra, duration of gout, presence of tophi or degree of control of hyperuricemia. Though crystals were found on rare occasions in joint fluid of asymptomatic hyperuricemic subjects, the presence of these crystals in asymptomatic joints was more common in subjects with gout.