The Magnetic Resonance Imaging-Linac System
The Magnetic Resonance Imaging-Linac System
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DOI：
10.1016/j.semradonc.2014.02.009
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发表时间：
2014-07-01
影响因子：
3.5
通讯作者：
van Vulpen, Marco
中科院分区：
文献类型：
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作者：
Lagendijk, Jan J. W.;Raaymakers, Bas W.;van Vulpen, Marco
目前的图像引导放射治疗系统在食管，胰腺，肾脏，直肠，淋巴结等中是次优的。这些位置在体内不容易获得基准，并且不能在锥形束计算机断层扫描上充分可视化，使得日常患者设置容易产生几何不确定性并阻碍剂量优化。这些位置的额外分次间和分次内不确定性来自呼吸和器官充盈的运动。为了在实际治疗位置对所有患者肿瘤位置进行实时成像，提供了一种完全集成的1.5 T诊断质量磁共振成像，采用6 MV直线加速器。该系统必须能够在所有身体部位进行详细的剂量绘制。(C)2014爱思唯尔公司All rights reserved.
The current image-guided radiotherapy systems are suboptimal in the esophagus, pancreas, kidney, rectum, lymph node, etc. These locations in the body are not easily accessible for fiducials and cannot be visualized sufficiently on cone-beam computed tomographies, making daily patient set-up prone to geometrical uncertainties and hinder dose optimization. Additional interfraction and intrafraction uncertainties for those locations arise from motion with breathing and organ filling. To allow real-time imaging of all patient tumor locations at the actual treatment position a fully integrated 1.5-T, diagnostic quality, magnetic resonance imaging with a 6-MV linear accelerator is presented. This system must enable detailed dose painting at all body locations. (C) 2014 Elsevier Inc. All rights reserved.