Direct determination of DNA twist-stretch coupling
Direct determination of DNA twist-stretch coupling
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DOI：
10.1209/epl/i1997-00231-y
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发表时间：
1996-11
期刊：
影响因子：
1.8
通讯作者：
R. Kamien;T. Lubensky;P. Nelson;C. O’Hern
中科院分区：
文献类型：
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作者：
R. Kamien;T. Lubensky;P. Nelson;C. O’Hern
DNA双螺旋结构的对称性需要一个新的术语来描述它对应力的线性反应：扭曲和拉伸之间的耦合。最近对受扭转约束的单分子进行的实验首次直接测量了这一重要的材料参数。我们从Strick et al. （Science, 271(1996) 1835）最近的实验中提取其值，并发现与Marko最近给出的独立实验估计一致。我们还提出了一个非常简单的微观理论，预测与观测值相当的值。
The symmetries of the DNA double helix require a new term in its linear response to stress: the coupling between twist and stretch. Recent experiments with torsionally constrained single molecules give the first direct measurement of this important material parameter. We extract its value from a recent experiment of Strick et al. (Science, 271 (1996) 1835) and find agreement with an independent experimental estimate recently given by Marko. We also present a very simple microscopic theory predicting a value comparable to the one observed.