Endoscopic gastric mucosal atrophy as a predictor of colorectal polyps: a large scale case-control study
Endoscopic gastric mucosal atrophy as a predictor of colorectal polyps: a large scale case-control study
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DOI：
10.3164/jcbn.19-47
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发表时间：
2019-09-01
影响因子：
2.4
通讯作者：
Murakami, Kazunari
中科院分区：
文献类型：
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作者：
Kawahara, Yoshinari;Kodama, Masaaki;Murakami, Kazunari
尽管一些研究表明幽门螺杆菌感染与结直肠肿瘤风险之间存在相关性，但这些发现并不一致且存在争议。本病例对照研究旨在探讨内镜下胃黏膜萎缩与结直肠息肉发生之间的关联。回顾性分析了2008年8月至2018年7月期间接受结肠镜检查的7394名参与者的记录。共登记了2404名受试者；1565名（65.1%）在胃黏膜萎缩阳性组，1138名（47.3%）患有结直肠息肉。通过年龄、性别、吸烟习惯、饮酒习惯、糖化血红蛋白和收缩压调整的多变量分析表明，与胃黏膜萎缩阴性组患者相比，胃黏膜萎缩阳性组患者更常患有结直肠息肉（优势比为3.27；95%置信区间为2.68 - 4.01；p<0.001）。（最后一个单词“p”后面应该还有内容，你可以补充完整以便我更好地为你服务）
Although some studies have indicated a correlation between Helicobacter pylori infection and the risk of colorectal neoplasms, these findings have not been consistent and are controversial. This case-control study aimed to investigate the association between endoscopic gastric mucosal atrophy and colorectal polyp occurrence. Records of 7,394 participants who underwent colonoscopy examinations from August 2008 to July 2018 were reviewed retrospectively. A total of 2,404 subjects were registered; 1,565 (65.1%) were in the gastric mucosal atrophy-positive group and 1,138 (47.3%) had colorectal polyps. The multivariate analysis adjusted by age, sex, smoking habits, alcohol habits, hemoglobin A1c, and systolic blood pressure indicated that patients in the gastric mucosal atrophy-positive group more frequently had colorectal polyps compared with patients in the gastric mucosal atrophy-negative group (odds ratio, 3.27; 95% confidence interval, 2.68-4.01; p