World Health Organization Global Estimates and Regional Comparisons of the Burden of Foodborne Disease in 2010.
World Health Organization Global Estimates and Regional Comparisons of the Burden of Foodborne Disease in 2010.
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DOI：
10.1371/journal.pmed.1001923
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发表时间：
2015-12
期刊：
影响因子：
15.8
通讯作者：
World Health Organization Foodborne Disease Burden Epidemiology Reference Group
中科院分区：
文献类型：
--
作者：
Havelaar AH;Kirk MD;Torgerson PR;Gibb HJ;Hald T;Lake RJ;Praet N;Bellinger DC;de Silva NR;Gargouri N;Speybroeck N;Cawthorne A;Mathers C;Stein C;Angulo FJ;Devleesschauwer B;World Health Organization Foodborne Disease Burden Epidemiology Reference Group
受污染食品引起的疾病和死亡是对公众健康的持续威胁，也是全世界社会经济发展的重大障碍。为了衡量食源性疾病（FBD）的全球和区域负担，世界卫生组织（WHO）成立了食源性疾病负担流行病学参考小组（FERG），该小组在此报告了他们对31种食源性危害的发病率，死亡率和疾病负担的首次估计。我们发现FBD的全球负担与主要传染病，艾滋病毒/艾滋病，疟疾和结核病的负担相当。食源性疾病最常见的原因是肠道病原体，特别是诺如病毒和弯曲杆菌属。腹泻病病原体，特别是非伤寒沙门氏菌，也是大多数FBD死亡的原因。其他导致FBD死亡的主要原因是伤寒沙门氏菌、猪带绦虫和甲型肝炎病毒。2010年，由31种危害造成的FBD的全球负担为3300万残疾调整生命年（DVDs）;五岁以下儿童承担了这一负担的40%。根据儿童和成人死亡率确定的14个次区域的家庭食物中毒负担差别很大，非洲次区域的负担最大，其次是东南亚次区域和东地中海D次区域。非伤寒S.肠道寄生虫是世界所有地区FBD的重要原因，而其他寄生虫，如某些寄生蠕虫，则高度局部化。因此，五岁以下儿童（尽管他们仅占全球人口的9%）和生活在世界低收入地区的人们尤其承受着FBD的负担。这些估计是保守的，即，低估而不是高估;需要进一步研究，以解决数据差距和研究的局限性。尽管如此，所有利益攸关方都可以通过将这些估计纳入国家和国际层面的政策制定，为改善整个食物链的食品安全做出贡献。全球食源性疾病概述;世界卫生组织调查食源性危害的发病率、死亡率和疾病负担的一部分。
Illness and death from diseases caused by contaminated food are a constant threat to public health and a significant impediment to socio-economic development worldwide. To measure the global and regional burden of foodborne disease (FBD), the World Health Organization (WHO) established the Foodborne Disease Burden Epidemiology Reference Group (FERG), which here reports their first estimates of the incidence, mortality, and disease burden due to 31 foodborne hazards. We find that the global burden of FBD is comparable to those of the major infectious diseases, HIV/AIDS, malaria and tuberculosis. The most frequent causes of foodborne illness were diarrheal disease agents, particularly norovirus and Campylobacter spp. Diarrheal disease agents, especially non-typhoidal Salmonella enterica, were also responsible for the majority of deaths due to FBD. Other major causes of FBD deaths were Salmonella Typhi, Taenia solium and hepatitis A virus. The global burden of FBD caused by the 31 hazards in 2010 was 33 million Disability Adjusted Life Years (DALYs); children under five years old bore 40% of this burden. The 14 subregions, defined on the basis of child and adult mortality, had considerably different burdens of FBD, with the greatest falling on the subregions in Africa, followed by the subregions in South-East Asia and the Eastern Mediterranean D subregion. Some hazards, such as non-typhoidal S. enterica, were important causes of FBD in all regions of the world, whereas others, such as certain parasitic helminths, were highly localised. Thus, the burden of FBD is borne particularly by children under five years old–although they represent only 9% of the global population–and people living in low-income regions of the world. These estimates are conservative, i.e., underestimates rather than overestimates; further studies are needed to address the data gaps and limitations of the study. Nevertheless, all stakeholders can contribute to improvements in food safety throughout the food chain by incorporating these estimates into policy development at national and international levels. An overview of foodborne diseases worldwide; part of the World Health Organization’s investigation into the incidence, mortality, and disease burden of foodborne hazards.