Placebo responding in the same direction as alcohol in women.
Placebo responding in the same direction as alcohol in women.
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安慰剂对女性的反应与酒精的反应相同。
DOI：
10.1111/j.1530-0277.1989.tb00280.x
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Newlin,DB
中科院分区：
文献类型：
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作者：
Newlin,DB
巴甫洛夫条件反射研究酒精在人类中已经进行了专门与男性受试者。男性表现出与酒精相反的安慰剂反应，Newlin（Alcohol Clin Exp Res 9411 - 416，1985）将其称为拮抗性安慰剂反应。目前的研究使用了正常女性受试者，给予酒精，安慰剂或软饮料控制。与对照条件相比，安慰剂显著（p< 0.05）增加心率，并且这种安慰剂反应与酒精的作用方向相同。女性心率变化与报告中毒的相关性为+0.44，而男性为负相关（Newlin DB Alcohol Clin Exp Rer 9：411 - 416，1985）。这些结果，当考虑到与其他数据有关的个体差异拮抗安慰剂反应，表明一种模式，其中酗酒的风险是负相关的安慰剂反应。
Pavlovian conditioning studies with alcohol in humans have been performed exclusively with men subjects. Men demonstrate a placebo response opposite in direction to alcohol, which Newlin (Alcohol Clin Exp Res 9411‐416, 1985) termed an antagonistic placebo response. The current study used normal women subjects given alcohol, placebo, or a soft drink control. Placebo significantly (p< 0.05) increased heart rate compared to the control condition, and this placebo response was in the same direction as the effect of alcohol. The correlation of heart rate change with reported intoxication was +0.44 in women, when it was negative in men (Newlin DB Alcohol Clin Exp Rer 9:411‐416, 1985). These results, when considered in relation to other data concerning individual differences in antagonistic placebo responding, suggest a pattern in which risk for alcoholism is negatively related to placebo responding.