URIC-ACID LEVELS IN SOUTHERN GERMANY IN 1989 - A COMPARISON WITH STUDIES FROM 1962, 1971, AND 1984
URIC-ACID LEVELS IN SOUTHERN GERMANY IN 1989 - A COMPARISON WITH STUDIES FROM 1962, 1971, AND 1984
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DOI：
10.1007/bf01796514
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发表时间：
1990-12-17
期刊：
影响因子：
--
通讯作者：
ZOLLNER, N
中科院分区：
文献类型：
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作者：
GRESSER, U;GATHOF, B;ZOLLNER, N
自 1962 年以来，我们的小组已对德国南部（巴伐利亚）献血者的尿酸值进行了四项研究。 多年来，男性尿酸水平有所增加，从 1962 年的 4.86 mg/dl 增加到 1971 年的 6.00 mg/dl，1984 年的 5.60 mg/dl，1989 年的 5.90 mg/dl。女性的尿酸水平略有增加，从 1962 年的 4.05 mg/dl 增加到 1971 年的 4.35 mg/dl。 1971年为4.10毫克/分升，1984年为4.10毫克/分升，1989年为4.16毫克/分升。51岁至60岁的女性尿酸水平明显高于40岁的女性。 在接受口服避孕药治疗的女性中，尿酸水平显着低于其他同龄女性。3名女性观察到低尿酸血症（尿酸水平小于或等于2.0 mg/dl），她们均无用药史。当尿酸水平大于或等于6.5 mg/dl时，即存在高尿酸血症。 1989年，2.6%的女性献血者和28.6%的男性献血者患有高尿酸血症，痛风、肾结石和肾病的风险增加。
Since 1962 our group has performed four studies on uric values in blood donors in southern Germany (Bavaria). Uric acid levels in men have increased over the years, from 4.86 mg/dl in 1962 to 6.00 mg/dl in 1971, 5.60 mg/dl in 1984, and 5.90 mg/dl in 1989. Levels in women have increased slightly, from 4.05 mg/dl in 1962 to 4.35 mg/dl in 1971, 4.10 mg/dl in 1984, and 4.16 mg/dl in 1989. Women aged 51 to 60 years had significantly higher uric acid levels than those in the fourth decade. In women treated with oral contraceptives uric acid levels were significantly lower than in other women of the same age.Hypouricemia (uric acid levels less-than-or-equal-to 2.0 mg/dl) was observed in three women, none of whom had a history of medication.Hyperuricemia exists when uric acid levels are greater-than-or-equal-to 6.5 mg/dl. In 1989 2.6% of the female blood donors and 28.6% of the males were hyperuricemic, with an increased risk of gout, nephrolithiasis, and nephropathy.