strcs: A command for fitting flexible parametric survival models on the log-hazard scale

strcs: A command for fitting flexible parametric survival models on the log-hazard scale
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DOI:
10.1177/1536867x1601600410
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发表时间:
2016-01-01
期刊:
影响因子:
4.8
通讯作者:
Lambert, Paul C.
Lambert, Paul C.
中科院分区:
数学3区
文献类型:
--
作者:
Bower, Hannah;Crowther, Michael J.;Lambert, Paul C.

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在本文中,我们描述了 strcs,这是一个用户编写的命令,用于在对数风险尺度上拟合灵活的参数生存模型。 strcs 是用户编写的 stgenreg 命令的扩展(Crowther 和 Lambert,2013b,Journal of Statistical Software 53(12):1-17),它使用数值积分将一般参数模型与用户定义的危险函数进行拟合。 strcs 实现了一种两步法,该方法结合了分析积分和数值积分来估计对数似然函数所需的累积风险函数。该方法提高了 stgenreg 中实现的完全数值估计的准确性。可以纳入时间依赖性效应,并且可以通过使用可用选项来拟合超额死亡率模型。我们还描述了一些在拟合 strcs 模型后可以轻松实现的广泛后估计命令。
In this article, we describe strcs, a user-written command for fitting flexible parametric survival models on the log-hazard scale. strcs is an extension of the user-written stgenreg command (Crowther and Lambert, 2013b, Journal of Statistical Software 53(12): 1-17), which fits general parametric models with user-defined hazard functions using numerical integration. strcs implements a two-step method that incorporates both analytical and numerical integration to estimate the cumulative hazard function required for the log-likelihood function. This method improves the accuracy of the fully numeric estimation implemented in stgenreg. Time-dependent effects can be incorporated, and excess mortality models can be fit by using the available options. We also describe some of the extensive postestimation commands that are easily implemented after fitting an strcs model.