Toward standardization of the cut-off value for the direct immunobead test using the postcoital test in immunologically infertile males.
Toward standardization of the cut-off value for the direct immunobead test using the postcoital test in immunologically infertile males.
复制标题
在免疫性不育男性中使用性交后测试来实现直接免疫珠测试的截止值的标准化。
DOI：
10.1007/s12522-012-0135-8
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发表时间：
2013
期刊：
影响因子：
3.4
通讯作者：
Mitsuaki Suzuki.
中科院分区：
文献类型：
--
作者：
Junko Koriyama;Hiroaki Shibahara;Tomoe Ikeda;Yuki Hirano;Tatsuya Suzuki;Mitsuaki Suzuki.
目的对直接免疫珠试验（D‐IBT）的截止值有进一步的认识。方法男性D - IBT阳性26例，D - IBT阴性140例。检查每个受试者的性交后测试（PCTs）结果。结果PCTs异常值< 20%与≥20%比较，差异有统计学意义（P= 0.02）。然而，异常pct值< 50%与≥50%之间无显著差异（P= 0.084）。结论截断值为20%与宫内人工授精治疗受孕的可能性相关。D - IBT是一种筛选试验，Bronson等人最初建议的20%的值似乎比世界卫生组织定义的50%的标准更合适。
PurposeThere is a need to improve our understanding of the cut‐off value of the direct immunobead test (D‐IBT).MethodsThe subjects were 26 D‐IBT‐positive and 140 D‐IBT‐negative males. The results of post coital tests (PCTs) for each subject were examined.ResultsA significant difference was observed in abnormal PCTs between values <20 % and those ≥20 % (P= 0.02). However, there was no significant difference in abnormal PCTs between values <50 % and those ≥50 % (P= 0.084).ConclusionsA cut‐off value of 20 % was correlated with the possibility of conception on treatment with IUI. The D‐IBT is a screening test, and the value of 20 % initially suggested by Bronson et al. seems to be more appropriate than that of 50 % in the criteria defined by the World Health Organization.