CHLORIDE FLUX IN BILAYER MEMBRANES - ELECTRICALLY SILENT CHLORIDE FLUX IN SEMISPHERICAL BILAYERS
CHLORIDE FLUX IN BILAYER MEMBRANES - ELECTRICALLY SILENT CHLORIDE FLUX IN SEMISPHERICAL BILAYERS
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DOI：
10.1021/bi00678a027
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发表时间：
1975-01-01
期刊：
影响因子：
2.9
通讯作者：
THOMPSON, TE
中科院分区：
文献类型：
--
作者：
TOYOSHIMA, Y;THOMPSON, TE
Yoshinori Toyoshima* 和 T. E. Thompson* 摘要：面积达 0.3 cm2 的高电阻半球形双层膜由合成二植烷酰磷脂酰胆碱的癸烷溶液形成。这些双层在 0.1 M KC1 中于 20 ℃时具有约 9 cm2 的比电阻和 0.38 µ cm-2 的比电容。在这些条件下，氯离子渗透率为 6.8 X 10-8 cm/sec。发现这种电静音 36C1 通量比根据系统电参数计算出的氯化物电流大约 103 倍。双层中的氯化物通量与所施加的电流无关
Yoshinori Toyoshima* and T. E. Thompson* abstract: High resistance semispherical bilayer mem-branes of areas as large as 0.3 cm2 were formed from a dec-ane solution of synthetic diphytanoylphosphatidylcholine. These bilayers had a specific resistance of about 9 cm2 and a specific capacitance of 0.38 µ cm-2 at 20 in 0.1 M KC1. Under these conditions, chloride permeability was 6.8 X 10-8 cm/sec. This electrically silent 36C1 flux was found to be about 103-fold larger than the chloride current calcu-lated from the electrical parameters of the system. The chloride flux in the bilayer was independent of the applied