Unusual choristoma of the parotid gland in a girl - A possible trichoadenoma

Unusual choristoma of the parotid gland in a girl - A possible trichoadenoma
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DOI:
10.1007/s004280050352
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发表时间:
1999-04-01
期刊:
VIRCHOWS ARCHIV-AN INTERNATIONAL JOURNAL OF PATHOLOGY
影响因子:
--
通讯作者:
Jautzke, G
Jautzke, G
中科院分区:
其他
文献类型:
--
作者:
Seifert, G;Donath, K;Jautzke, G

文献摘要

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一个8岁的女孩有一个无痛的局限性结节在右侧腮腺4周。唾液腺实质内的肿瘤(直径1.3 cm)在肉眼下显示小囊性空间和角状物质。肿瘤组织包含固体鳞状细胞形成和囊性空间有限的多层鳞状上皮和覆盖层的正角化和角化不全的细胞。囊性空间包含角化板层。部分区域可见上皮细胞针样增生,上皮细胞核均一,未见不典型核分裂。间质组织中偶见角化肿块伴部分钙化,并被多核巨细胞所取代。肿瘤被归类为绒毛膜瘤,类似于腺瘤。外胚层来源的口腔和唾液腺上皮可能是皮肤样或附件性谣言的来源。
An 8-year-old girl had a painless circumscribed nodule in the right parotid gland for 4 weeks. A tumour (1.3 cm diameter) within the salivary gland parenchyma showed small cystic spaces with horn-like material macroscopically. The tumour tissue contained solid squamous cell formations and cystic spaces limited by multilayered squamous epithelium and covered by layers of ortho- and parakeratotic cells. The cystic spaces contained keratotic lamellae. In some areas pin-like epithelial proliferations were seen, All epithelial cells were characterized by uniform nuclei, and no atypical mitoses were seen. Keratinizated masses with partial calcification were occasionally located in the interstitial tissue and replaced by multinucleated giant cells. The tumour was classified as a choristoma and resembled a trichoadenoma. The ectodermally derived oral and salivary gland epithelium may be the source of skin-like or adnexal rumours.