UPPER-BODY FAT DISTRIBUTION - A HYPERINSULINEMIA-INDEPENDENT PREDICTOR OF CORONARY HEART-DISEASE MORTALITY - THE PARIS PROSPECTIVE-STUDY

UPPER-BODY FAT DISTRIBUTION - A HYPERINSULINEMIA-INDEPENDENT PREDICTOR OF CORONARY HEART-DISEASE MORTALITY - THE PARIS PROSPECTIVE-STUDY
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DOI:
10.1161/01.atv.12.12.1387
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发表时间:
1992-12-01
期刊:
ARTERIOSCLEROSIS AND THROMBOSIS
影响因子:
--
通讯作者:
ESCHWEGE, E
ESCHWEGE, E
中科院分区:
其他
文献类型:
--
作者:
CASASSUS, P;FONTBONNE, A;ESCHWEGE, E

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巴黎前瞻性研究是一项在大量中年男性人群中对冠心病预测因素的长期调查。第一次随访检查涉及7,152名受试者,他们是法国本土人,没有任何心血管病史。同时,记录常见的心血管危险因素和血浆胰岛素水平。身体脂肪分布的指数,髂股比,被列入预测变量列表,尽管它已经测量了1年前的第一次随访检查。平均随访11年后,129名男性死于冠心病。单因素分析显示,髂股比(p
The Paris Prospective Study is a long-term investigation of the factors predicting coronary heart disease in a large population of middle-aged men. The first follow-up examination involved 7,152 subjects, who were natives of metropolitan France and were free of any cardiovascular history. At that time, the usual cardiovascular risk factors and plasma insulin levels were recorded. An index of body fat distribution, the iliac-to-thigh ratio, was entered into the list of predictive variables, despite the fact that it had been measured 1 year before the first follow-up examination. After 11 years of mean follow-up, 129 of the men had died of coronary heart disease. Univariate analysis showed that the iliac-to-thigh ratio (p