UPPER-BODY FAT DISTRIBUTION - A HYPERINSULINEMIA-INDEPENDENT PREDICTOR OF CORONARY HEART-DISEASE MORTALITY - THE PARIS PROSPECTIVE-STUDY
UPPER-BODY FAT DISTRIBUTION - A HYPERINSULINEMIA-INDEPENDENT PREDICTOR OF CORONARY HEART-DISEASE MORTALITY - THE PARIS PROSPECTIVE-STUDY
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DOI:
10.1161/01.atv.12.12.1387
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发表时间:
1992-12-01
期刊:
影响因子:
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通讯作者:
ESCHWEGE, E
中科院分区:
文献类型:
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作者:
CASASSUS, P;FONTBONNE, A;ESCHWEGE, E
The Paris Prospective Study is a long-term investigation of the factors predicting coronary heart disease in a large population of middle-aged men. The first follow-up examination involved 7,152 subjects, who were natives of metropolitan France and were free of any cardiovascular history. At that time, the usual cardiovascular risk factors and plasma insulin levels were recorded. An index of body fat distribution, the iliac-to-thigh ratio, was entered into the list of predictive variables, despite the fact that it had been measured 1 year before the first follow-up examination. After 11 years of mean follow-up, 129 of the men had died of coronary heart disease. Univariate analysis showed that the iliac-to-thigh ratio (p