Practical model description of peripheral neural excitation in cochlear implant recipients: 3. ECAP during bursts and loudness as function of burst duration
Practical model description of peripheral neural excitation in cochlear implant recipients: 3. ECAP during bursts and loudness as function of burst duration
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DOI：
10.1016/j.heares.2008.11.002
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发表时间：
2009-01-20
期刊：
影响因子：
2.8
通讯作者：
Cohen, Lawrence T.
中科院分区：
文献类型：
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作者：
Cohen, Lawrence T.
在这篇系列论文的第三篇中，我们测量了植入了Nucleus‘24人工耳蜗系统的受试者的低频率电脉冲的响度，作为脉冲持续时间的函数(其中三个植入了STREAT，两个植入了Conour(TM)电极阵列)。为了帮助区分外周效应和更多中枢效应的作用，使用神经反应遥测(TM)(NRT(TM))系统将ECAP记录到组成脉冲的单个脉冲上。在脉搏频率为250脉冲/S时，电刺激诱发电位幅度下降不大，平均下降系数为0.89。由脉冲组成的脉冲的响度贡献的总和的时间常数被发现大于与正常听力相关的时间常数。此外，尽管在ECAP记录中没有观察到相应的差异，但发现脉冲序列的第一个脉冲对总体响度的贡献比随后的脉冲要大得多。这些结果在本系列第四和第五篇论文中提出的基本上是单脉冲的模型与脉搏爆发的心理物理数据之间建立了必要的联系，但它们也具有更广泛的影响。(C)2008爱思唯尔B.V.保留所有权利。
In this, the third paper of the series, the loudness of low-rate bursts of electrical pulses was measured as a function of the burst duration, in subjects implanted with the Nucleus' 24 cochlear implant system (three with straight and two with Contour (TM) electrode arrays). In order to help distinguish between the contributions of peripheral and more central effects, the ECAP was recorded to the individual pulses comprising the bursts, using the Neural Response Telemetry (TM) (NRT (TM)) system. At a pulse rate of 250 pulses/s, the ECAP amplitude did not decrease greatly during the bursts: the mean reduction factor was 0.89. The time-constant for summation of the loudness contributions from the pulses comprising a burst was found to be larger than that associated with normal hearing. In addition, the first pulse of a pulse train was found to contribute much more to the overall loudness than did the subsequent pulses, although a corresponding difference was not observed in the ECAP recordings. These results establish a necessary connection between the essentially single-pulse model, developed in the fourth and fifth papers of the series, and the psychophysical data for pulse bursts, but they also have broader implications. (c) 2008 Elsevier B.V. All rights reserved.