α-Mannosidase in Zinc-Deficient Rats: Possibility of Liposomal Therapy in Mannosidosis
α-Mannosidase in Zinc-Deficient Rats: Possibility of Liposomal Therapy in Mannosidosis
复制标题
缺锌大鼠中的 α-甘露糖苷酶：脂质体治疗甘露糖苷中毒的可能性
DOI：
10.1042/bst0021014
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发表时间：
1974
影响因子：
3.9
通讯作者：
B. E. Ryman
中科院分区：
文献类型：
--
作者：
H. Patel;B. E. Ryman
已证实α-甘露糖苷酶存在于包括人在内的许多哺乳动物组织中（Conchie & Hay，1959; Ockerman，1969）。已显示溶酶体α-甘露糖苷酶活性是Zn 2+依赖性的，并且被EDTA灭活（Snaith & Levvy，1969）。中性α-甘露糖苷酶也被EDTA抑制，但其活性
The presence of a-mannosidase has been demonstrated in many mammalian tissues including man (Conchie & Hay, 1959; Ockerman, 1969). Lysosomal a-mannosidase activity has been shown to be Znz+-dependent and to be inactivated by EDTA (Snaith & Levvy, 1969). The neutral a-mannosidase is also inhibited by EDTA, but its activity