Potentially Poisonous Plastic Particles: Microplastics as a Vector for Cyanobacterial Toxins Microcystin-LR and Microcystin-LF
Potentially Poisonous Plastic Particles: Microplastics as a Vector for Cyanobacterial Toxins Microcystin-LR and Microcystin-LF
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DOI：
10.1021/acs.est.1c05796
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发表时间：
2021-12-07
影响因子：
11.4
通讯作者：
Lawton, Linda A.
中科院分区：
文献类型：
--
作者：
Pestana, Carlos J.;Moura, Diana S.;Lawton, Linda A.
微塑料作为自然或人为来源的微污染物载体的可能性日益受到关注。蓝藻毒素，包括微囊藻毒素，对人类和野生动物有害。在这项研究中，我们首次证明了微塑料作为两种不同微囊藻毒素类似物载体的潜力。聚苯乙烯和微囊藻毒素-LF的组合在塑料上的毒素浓度为142 +/- 7 μ g/g（-1），观察到从水到塑料的浓度高达28倍。根据实验结果，并假设最坏的情况下，水蚤的潜在毒素剂量是根据公布的微塑料摄入数据计算的。从理论上讨论了微囊藻毒素在生物体中的浓度。实验结果表明，微囊藻毒素吸附到微塑料上是一个多因素的过程，取决于颗粒大小、微囊藻毒素的可变氨基酸组成、塑料类型和pH。此外，目前的研究结果强调了专门研究微囊藻毒素LR的局限性（最常研究的微囊藻毒素同系物）作为代表一组约250种已报告的微囊藻毒素同系物的模型化合物。
The potential of microplastics to act as a vector for micropollutants of natural or anthropogenic origin is of rising concern. Cyanobacterial toxins, including microcystins, are harmful to humans and wildlife. In this study, we demonstrate for the first time the potential of microplastics to act as vectors for two different microcystin analogues. A concentration of up to 28 times from water to plastic was observed for the combination of polystyrene and microcystin-LF achieving toxin concentrations on the plastic of 142 +/- 7 mu g g(-1). Based on the experimental results, and assuming a worst-case scenario, potential toxin doses for daphnids are calculated based on published microplastic ingestion data. Progressing up through trophic levels, theoretically, the concentration of microcystins in organisms is discussed. The experimental results indicate that adsorption of microcystins onto microplastics is a multifactorial process, depending on the particle size, the variable amino acid composition of the microcystins, the type of plastic, and pH. Furthermore, the results of the current study stressed the limitations of exclusively investigating microcystin-LR (the most commonly studied microcystin congener) as a model compound representing a group of around 250 reported microcystin congeners.