EFFECTS OF GONADAL HORMONES ON URINARY BEHAVIOR IN DOGS

EFFECTS OF GONADAL HORMONES ON URINARY BEHAVIOR IN DOGS
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DOI:
10.1016/0031-9384(74)90148-6
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发表时间:
1974-01-01
影响因子:
2.9
通讯作者:
BEACH, FA
BEACH, FA
中科院分区:
医学3区
文献类型:
--
作者:
BEACH, FA

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研究了8组犬睾丸和卵巢激素对尿频和尿姿的影响。四组女性中有三组在子宫内、新生儿时或在子宫和婴儿期都接受过雄激素刺激。第四组为切除卵巢的对照组。雄性在成年、幼年或刚出生时被阉割或完好无损。雌激素组和睾酮组的排尿次数均增加。在成年或幼年阶段阉割后,男性的排尿姿势不受影响。雄性的新生儿阉割导致从成年男性姿势到未成熟男性姿势的周期性回归。对照组和产前雄激素化的雌性以女性体位排尿。在婴儿期接受大量睾酮治疗的雌性显示出有限程度的尿姿男性化。在出生前后暴露于睾酮的女性大约有50%的时间是女性排尿,而成年男性排尿的时间约为一半。外源性雌激素或雄激素给药在成年没有影响排尿姿势。
The effects of testicular and ovarian hormones on urinary frequency and posture were studied in 8 groups of dogs. Three of the 4 female groups had been exposed to androgenic stimulation in utero, neonatally, or both in utero and in infancy. The fourth group of females consisted of ovariectomized controls. Males were intact or castrated as adults, as juveniles, or as neonates. Frequency of urination was increased in all groups by estrogen and by testosterone. Urinary posture was unaffected in males by castration in the adult or juvenile stages. Neonatal castration of males resulted in periodic regression from the adult male posture to the immature male posture. Control and prenatally androgenized females urinated in the feminine position. Females treated with large amounts of testosterone in infancy showed a limited degree of masculinization of urinary posture. Females exposed to testosterone before and immediately after birth urinated as females about 50% of the time and as adult males for approximately half of their urinations. Exogenous estrogen or androgen administered in adulthood had no effect on posture assumed for urination.