The effects of state of alertness on the vestibulo-ocular reflex in normal subjects using the vestibular rotational chair.
The effects of state of alertness on the vestibulo-ocular reflex in normal subjects using the vestibular rotational chair.
复制标题
使用前庭旋转椅的正常受试者的警觉状态对前庭眼反射的影响。
DOI：
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发表时间：
2004
影响因子：
2.3
通讯作者：
J. Enticott
中科院分区：
文献类型：
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作者：
F. V. Matta;J. Enticott
24 名前庭功能正常的受试者接受了两次水平正弦谐波加速度 (SHA) 和步进速度旋转椅评估，第一次处于高度警觉状态，第二次处于低警觉状态。然后检查警觉性对前庭眼反射增益和时间常数（Tc）的影响。尽管之前已广泛报道了对 SHA 增益的负面影响，但尚未研究对 Tc 的影响。结果发现，随着警觉性的降低，SHA 增益和步速 Tc 显着且人为地降低。平均而言，每个测试频率下 SHA 增益减少 0.1，Tc 从 15.8 秒减少到 10.5 秒。平均而言，步速初始增益仅受到轻微影响，从 0.53 降至 0.49。这个 0.04 的微小差异是显着的，然而，它表明该测量值比 SHA 增益和 Tc 受患者警觉性的影响更小。
Twenty-four subjects with normal vestibular function underwent horizontal sinusoidal harmonic acceleration (SHA) and step-velocity rotational chair assessment twice, first in a heightened state-of-alertness, and second, in a low state-of-alertness. The effects of alertness on vestibulo-ocular reflex gain and time-constant (Tc) were then examined. Although the negative effect on SHA gain had previously been widely reported, the effect on the Tc had not been studied. It was found that SHA gain and step-velocity Tc were significantly and artificially reduced with decreased alertness. On average, SHA gain was reduced by 0.1 at each test frequency and the Tc was reduced from 15.8 seconds to 10.5 seconds. Whilst on average, step-velocity initial gain was only a little affected reducing from 0.53 to 0.49. This very small difference of 0.04 was significant, however, it suggested that this measurement is less affected by patient alertness than SHA gain and Tc.