Prenylbicyclogermacrane diterpenoids from the formosan soft coral Nephthea pacifica
Prenylbicyclogermacrane diterpenoids from the formosan soft coral Nephthea pacifica
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DOI：
10.1021/np040160e
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发表时间：
2005-01-01
影响因子：
5.1
通讯作者：
Duh, CY
中科院分区：
文献类型：
--
作者：
El-Gamal, AAH;Wang, SK;Duh, CY
从台湾软珊瑚Nephthea pacifica的二氯甲烷可溶物中分离得到10个新的异戊二烯基双环吉马烷二萜化合物，命名为pacificins A-J（1-10）。通过1D和2D NMR光谱分析阐明了结构，并在体外测量了它们对所选癌细胞的细胞毒性。
Ten new prenylbicyclogermacrane diterpenoids, pacificins A-J (1-10), were isolated from the methylene chloride solubles of the Formosan soft coral Nephthea pacifica. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.