Considerations in the Treatment of Geriatric Depression Overview of Pharmacotherapeutic and Psychotherapeutic Treatment Interventions

Considerations in the Treatment of Geriatric Depression Overview of Pharmacotherapeutic and Psychotherapeutic Treatment Interventions
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DOI:
10.3928/19404921-20100526-01
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发表时间:
2010-07-01
影响因子:
1.6
通讯作者:
Sadowski, Cheryl A.
Sadowski, Cheryl A.
中科院分区:
医学4区
文献类型:
--
作者:
Rojas-Fernandez, Carlos H.;Miller, Lisa J.;Sadowski, Cheryl A.

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老年(或晚年)抑郁症在老年人中很常见,在70至85岁之后,以及在住院和住在养老院的人中,发病率急剧增加。在这一人群中,抑郁症促进残疾,并与共病慢性医学疾病的恶化结果相关。由于各种原因,包括(错误地)认为抑郁症是衰老的正常组成部分,在初级保健机构中,老年抑郁症往往未被发现或治疗不足。目前的研究表明,虽然老年人使用抗抑郁药物的质量正在提高,但仍有改进的空间。改善老年人抑郁症的药物治疗需要对许多临床因素的认识和理解。本综述的目的是讨论老年抑郁症的突出问题,重点是药物治疗和心理治疗干预。
Geriatric (or late-life) depression is common in older adults, with an incidence that increases dramatically after age 70 to 85, as well as among those admitted to hospitals and those who reside in nursing homes. In this population, depression promotes disability and is associated with worsened outcomes of comorbid chronic medical diseases. Geriatric depression is often undetected or undertreated in primary care settings for various reasons, including the (incorrect) belief that depression is a normal part of aging. Current research suggests that while antidepressant agent use in older adults is improving in quality, room for improvement exists. Improving the pharmacotherapy of depression in older adults requires knowledge and understanding of many clinical factors. The purpose of this review is to discuss salient issues in geriatric depression, with a focus on pharmacotherapeutic and psychotherapeutic interventions.