Ovarian cancer: Changes in patterns at diagnosis and relative survival over the last three decades
Ovarian cancer: Changes in patterns at diagnosis and relative survival over the last three decades
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DOI：
10.1067/s0002-9378(03)00579-9
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发表时间：
2003-10-01
影响因子：
9.8
通讯作者：
Munkarah, AR
中科院分区：
文献类型：
--
作者：
Barnholtz-Sloan, JS;Schwartz, AG;Munkarah, AR
目的：本研究的目的是检查1973年至1997年诊断为原发性浸润性上皮性卵巢癌（EOC）的女性的诊断模式和相对生存率，并随访至1999年底。研究设计：从人口为基础的监测，流行病学和最终结果（SEER）计划，32,845名妇女诊断1973年和1997年之间用于分析。研究人群被分为三个队列的基础上，年的诊断和队列进行比较，就使用卡方检验和相对生存分析的寿命表方法的利益变量。结果：有一个增加的比例，少数民族诊断为卵巢上皮性癌，妇女60岁或以上的诊断，并随着时间的推移接受手术的妇女。随着时间的推移，生存率不断提高，虽然老年患者（60岁或以上）和非洲裔美国人继续有最差的survival.CONCLUSION：随着时间的推移，相对生存的妇女有原发性侵入性卵巢癌诊断改善。
OBJECTIVE: The purpose of this study was to examine patterns of diagnosis and relative survival in women who had a diagnosis of primary invasive epithelial ovarian cancer (EOC) from 1973 to 1997, with follow-up through the end of 1999.STUDY DESIGN: From the population-based Surveillance, Epidemiology and End Results (SEER) Program, 32,845 women diagnosed between 1973 and 1997 were used for analysis. The study population was divided in three cohorts based on year of diagnosis and the cohorts were compared with respect to variables of interest by using chi(2) tests and relative survival analysis by the life table method.RESULTS: There was an increase in the proportions of minorities diagnosed with EOC, of women 60 years or older at diagnosis, and of women undergoing surgery over time. Survival continuously improved over time, although older patients (60 years or older) and African Americans continued to have the poorest survival.CONCLUSION: Over time, relative survival of women who had primary invasive EOC diagnosed improved.