Efficacy of interpersonal psychotherapy for postpartum depression
Efficacy of interpersonal psychotherapy for postpartum depression
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DOI：
10.1001/archpsyc.57.11.1039
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发表时间：
2000-11-01
影响因子：
--
通讯作者：
Wenzel, A
中科院分区：
文献类型：
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作者：
O'Hara, MW;Stuart, S;Wenzel, A
背景：产后抑郁症给妇女造成巨大痛苦，对其社会关系和婴儿发育造成负面影响，需要研究来评价心理治疗对产后抑郁症的疗效。方法：从社区招募120名符合DSM-TV抑郁症诊断标准的产后抑郁妇女，随机分为人际心理治疗(IPT)和等待名单条件(WLC)对照组，治疗12周。研究对象每4周完成一次抑郁症状和社会适应的访谈和自我报告。结果：120例患者中99例完成了治疗方案。接受IPT的女性汉密尔顿抑郁量表(HRSD)得分从19.4降至8.3，降幅明显大于WLC组(19.8至16.8)。接受IPT的妇女的Beck抑郁指数(BDI)得分在12周内从23.6下降到10.6，比WLC组(23.0到19.2)的下降幅度要大得多。接受IPT治疗的女性中，HRSD评分为6分或更低(37.5%)和BDI评分为9分或更低(43.8%)的女性从抑郁发作中恢复的比例显著高于WLC组(分别为13.7%和13.7%)。接受IPT治疗的产妇在产后适应问卷和社会适应自评量表上的得分也明显高于WLC组。结论：IPT是一种治疗产后抑郁症的有效方法。人际心理疗法减少了抑郁症状，改善了社会适应，是药物疗法的替代疗法，特别是对正在哺乳的妇女。
Background: Postpartum depression causes women great suffering and has negative consequences for their social relationships and for the development of their infants, Research is needed to evaluate the efficacy of psychotherapy for postpartum depression.Methods: A total of 120 postpartum women meeting DSM-TV criteria for major depression were recruited from the community and randomly assigned to 12 weeks of interpersonal psychotherapy (IPT) or to a waiting list condition (WLC) control group. Subjects completed interview and self-report assessments of depressive symptoms and social adjustment every 4 weeks.Results: Ninety-nine of the 120 patients completed the protocol. Hamilton Raring Scale for Depression (HRSD) scores of women receiving IPT declined from 19.4 to 8.3, a significantly greater decrease than occurred in the WLC group (19.8 to 16.8). The Beck Depression Inventory (BDI) scores of women who received IPT declined from 23.6 to 10.6 over 12 weeks, a significantly greater decrease than occurred in the WLC group (23.0 to 19.2). A significantly greater proportion of women who received IPT recovered from their depressive episode based on HRSD scores of 6 or lower (37.5%) and BDI scores of 9 or lower (43.8%) compared with women in the WLC group (13.7% and 13.7%, respectively). Women receiving IPT also had significant improvement on the Postpartum Adjustment Questionnaire and the Social Adjustment Scale-Self-Report relative to women in the WLC group.Conclusions: These findings suggest that IPT is an efficacious treatment for postpartum depression. Interpersonal psychotherapy reduced depressive symptoms and improved social adjustment, and represents an alternative to pharmaco therapy, particularly for women who are breastfeeding.