Issues with using baseline in last observation carried forward analysis
Issues with using baseline in last observation carried forward analysis
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DOI：
10.1002/pst.311
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发表时间：
2008-04-01
影响因子：
1.5
通讯作者：
Mullee, Mark A.
中科院分区：
文献类型：
--
作者：
Julious, Steven A.;Mullee, Mark A.
这篇论文的主题是由一项研究引起的，我们中的一位是统计学家。它被提交给内科医学年鉴。该论文得到了积极的评审意见;然而，统计评审员表示，为了使分析可接受用于发表，必须通过在末次观察值结转插补中使用基线在分析中解释缺失数据。我们讨论了与这种插补形式相关的问题，并建议不应将其作为主要分析。版权所有（C）2007约翰威利父子有限公司
The topic of this paper was prompted by a study for which one of us was the statistician. It was submitted to Annals of Internal Medicine. The paper had positive reviewer comment; however, the statistical reviewer stated that for the analysis to be acceptable for publication, the missing data had to be accounted for in the analysis through the use of baseline in a last observation carried forward imputation. We discuss the issues associated with this form of imputation and recommend that it should not be undertaken as a primary analysis. Copyright (C) 2007 John Wiley & Sons, Ltd.