Polarized Light Colposcopy Compared With Standard Colposcopy.
Polarized Light Colposcopy Compared With Standard Colposcopy.
复制标题
偏振光阴道镜与标准阴道镜的比较。
DOI：
10.1097/lgt.0000000000000111
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发表时间：
2015
影响因子：
3.7
通讯作者：
Goebel,Angela
中科院分区：
文献类型：
--
作者：
Ferris,DaronG;Condorhuaman,WendyShulayGuevara;Waller,JenniferL;Allmond,Lynn;Goebel,Angela
本研究的目的是确定潜在的好处偏振光阴道镜检查相比，标准阴道镜检查在评估妇女异常宫颈cytology.Materials和MethodsPolarized和标准阴道镜检查进行了330例。获得相应的图像和活检注释。灵敏度和特异性;宫颈肿瘤严重程度的差异;阴道镜检查结果、活检目的和活检部位的一致性;结果非偏振光和偏振光阴道镜对病变的敏感性和特异性分别为96.8%和64.5%，分别为96.8%和64.9%。在非偏振（80.7）和偏振（80.9）阴道镜检查之间观察到的病变的ROC无统计学显著差异。同样，非偏振阴道镜检查（80.2）和偏振阴道镜检查（78.8）之间的活检意向ROC无统计学显著差异。非偏振和偏振阴道镜检查的宫颈病理学与阴道镜检查结果的一致性分别为0.986和0.952。非偏振和偏振阴道镜检查中看到的病变的平均数量或拟活检的网站数之间没有显着差异。ConclusionsPolarized光阴道镜检查是没有用的辅助传统阴道镜检查在这项研究中。需要进行进一步的研究，以确定偏振光阴道镜在临床实践中的整体效用。
ObjectiveThe objective of this study was to determine the potential benefits of polarized light colposcopy compared with standard colposcopy examinations in the evaluation of women with abnormal cervical cytology.Materials and MethodsPolarized and standard colposcopy examinations were performed on 330 subjects. Respective images and biopsy annotations were obtained. Sensitivity and specificity; differences in the severity of cervical neoplasia; agreement of colposcopy impression, biopsy intent, and biopsy site; and differences in the number of biopsies were determined using the ROC, Bowker’s test of symmetry, kappa statistic, and paired t test, respectively.ResultsThe sensitivity and specificity for a lesion being seen with nonpolarized light and polarized light colposcopy were 96.8% and 64.5%, and 96.8% and 64.9%, respectively. There was no statistically significant difference in the ROC of the lesion being seen between nonpolarized (80.7) and polarized (80.9) colposcopy. Likewise, there was no statistically significant difference in the ROC of intent to biopsy between nonpolarized (80.2) and polarized colposcopy (78.8). The agreement of cervical histopathology and colposcopy impression for nonpolarized and polarized colposcopy were 0.986 and 0.952, respectively. There was no significant difference between nonpolarized and polarized colposcopy in the mean number of lesions seen or number of sites intended to biopsy.ConclusionsPolarized light colposcopy was not useful as an adjunct to conventional colposcopy in this study. Further research needs to be performed to determine the overall utility of polarized light colposcopy in clinical practice.