Carotid artery: elliptic centric contrast-enhanced MR angiography compared with conventional angiography.
Carotid artery: elliptic centric contrast-enhanced MR angiography compared with conventional angiography.
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DOI：
10.1148/radiology.218.1.r01ja41138
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发表时间：
2001
期刊：
影响因子：
19.7
通讯作者：
J. Huston;S. Fain;J. Wald;P. Luetmer;C. Rydberg;Diego J. Covarrubias;S. Riederer;Matt A. Bernstein;Robert D. Brown;F. Meyer;T. Bower;C. Schleck
中科院分区：
文献类型：
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作者：
J. Huston;S. Fain;J. Wald;P. Luetmer;C. Rydberg;Diego J. Covarrubias;S. Riederer;Matt A. Bernstein;Robert D. Brown;F. Meyer;T. Bower;C. Schleck
目的以常规磁共振血管造影为参考标准，评价椭圆中心对比剂增强磁共振血管造影的准确性。材料与方法对50例患者进行对比增强磁共振血管造影和常规血管造影检查。两次检查在1周内进行。两名患者仅对一条颈动脉进行了常规血管造影，获得了98条动脉用于比较。结果以常规血管造影为参考标准，以颈内动脉内径狭窄为70%阈值，最大密度投影（MIP）图像诊断颈内动脉狭窄的敏感性为93.3%，特异性为85.1%，准确性为87.6%;常规血管造影片的观察者间变异性为0.97，MIP图像为0.91，源图像为0.90。对比增强MR血管造影技术对不规则和/或溃疡的敏感性为88.9%，特异性为58.1%。所有50次检查均被适当触发，因此描绘的静脉信号强度极小或无。结论：对比增强椭圆中心三维MR血管造影提供了高空间分辨率，静脉抑制图像的颈动脉，似乎是足够的，以取代传统的血管造影术在大多数患者颈动脉内膜切除术前检查。
PURPOSE To determine the accuracy of elliptic centric contrast material-enhanced magnetic resonance (MR) angiography by using conventional angiography as the reference standard. MATERIALS AND METHODS Fifty patients were examined prospectively with contrast-enhanced MR angiography and conventional angiography. The two examinations were performed within 1 week of each other. Two patients underwent conventional angiography of only one carotid artery, which yielded 98 arteries for comparison. RESULTS With conventional angiography as the reference standard and by using a 70% threshold for internal carotid arterial diameter stenosis, maximum intensity projection (MIP) images had a sensitivity of 93.3%, specificity of 85.1%, and accuracy of 87.6%, whereas reformatted transverse source images had a sensitivity of 83.3%, specificity of 97.0%, and accuracy of 92.8%. Interobserver variability for conventional angiograms was 0.97, for MIP images was 0.91, and for source images was 0.90. The contrast-enhanced MR angiographic technique had a sensitivity of 88.9% and specificity of 58.1% for the presence of irregularity and/or ulceration. All 50 examinations were triggered appropriately so that minimal or no venous signal intensity was depicted. CONCLUSION Contrast-enhanced elliptic centric three-dimensional MR angiography offers high-spatial-resolution, venous-suppressed images of the carotid arteries that appear to be adequate to replace conventional angiography in most patients examined prior to carotid endarterectomy.