Papuloerythroderma of Ofuji associated with sternoclavicular arthritis and successful treatment with cyclosporine.
Papuloerythroderma of Ofuji associated with sternoclavicular arthritis and successful treatment with cyclosporine.
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DOI：
10.1016/j.jdcr.2022.07.004
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发表时间：
2022-09
影响因子：
--
通讯作者：
Yamanaka, Keiichi
中科院分区：
文献类型：
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作者：
Kasai, Eri;Habe, Koji;Matsushima, Yoshiaki;Kondo, Makoto;Yamanaka, Keiichi
Ofuji丘疹性红皮病的特征是多边形、平顶、褐色丘疹，这些丘疹合并成片状，通常覆盖整个皮肤表面，但在大的擦破区域（如腹部、肘前窝、腘窝和腹股沟区）没有皮疹，称为甲板椅征。丘疹性红皮病可能是药物引起的或原发性的;然而，它可能是恶性肿瘤背景下的副肿瘤发现。与丘疹性红皮病相关的肿瘤疾病包括胃癌、肝细胞癌、腺癌和皮肤T细胞淋巴瘤。1胸锁关节炎通过放射学、计算机断层扫描、磁共振成像和骨显像进行评估。早期诊断和治疗是至关重要的，因为胸锁关节炎可能会发展为不可逆的骨和关节损伤。风湿性关节炎、脊柱关节炎（SpA）、SAPHO（滑膜炎、痤疮、脓疱病、骨质增生、骨炎）综合征和掌跖脓疱病（PPP）是引起胸锁关节炎的众所周知的疾病。在SAPHO综合征中，骨显像上胸锁关节和胸骨角的高示踪剂摄取的“牛头”模式是特异性的。二、三
Papuloerythroderma of Ofuji is characterized by polygonal, flat-topped, erythematous-brown papules that coalesce into sheets that often cover the entire skin surface but without skin rash in large intertriginous areas such as the abdomen, antecubital fossa, popliteal fossa, and inguinal area, called as the deck-chair sign. Papuloerythroderma may be drug-induced or primary; however, it can be a paraneoplastic finding in the setting of malignancy. The range of oncotic disorders found in association with papuloerythroderma includes gastric carcinomas, hepatocellular carcinoma, adenocarcinoma, and cutaneous T-cell lymphoma. 1Sternoclavicular arthritis is evaluated using radiography, computed tomography, magnetic resonance imaging, and bone scintigraphy. Early diagnosis and treatment are critical because sternoclavicular arthritis may progress to irreversible bone and joint damage. Rheumatoid arthritis, spondyloarthritis (SpA), SAPHO (synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome, and palmoplantar pustulosis (PPP) are well-known diseases that cause sternoclavicular arthritis. In SAPHO syndrome, the “bull's head” pattern of high tracer uptake in the sternoclavicular joint and angulus sterni on bone scintigraphy are specific. 2, 3